Active Recombinant Human IDO1 protein, His-tagged
Cat.No. : | IDO1-008H |
Product Overview : | Active recombinant human N-terminal His-tagged IDO1 was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | 40 mM Tris-HCl, pH 8.0, with 110 mM sodium chloride, 2.2 mM potassium chloride, and 20% glycerol. |
Bio-activity : | IDO1 activity is measured by incubating with L-Trp substrate. After a three hour roomtemperature incubation, activity is determined by measuring the absorption of reaction product at λ = 320-325 nm. |
Molecular Mass : | 46 kDa |
Protein length : | 2-403 (full length) |
Purity : | ≥90% estimated by SDS-PAGE |
Applications : | Enzyme Activity |
Stability : | ≥ 6 months |
Storage : | -80 centigrade |
Shipping : | Dry ice in continental US; may vary elsewhere |
Gene Name : | IDO1 indoleamine 2,3-dioxygenase 1 [ Homo sapiens (human) ] |
Official Symbol : | IDO1 |
Synonyms : | Indoleamine 2,3-dioxygenase 1 Indoleamine-pyrrole 2,3-dioxygenase |
Gene ID : | 3620 |
mRNA Refseq : | NM_002164 |
Protein Refseq : | NP_002155 |
MIM : | 147435 |
UniProt ID : | P14902 |
Products Types
◆ Recombinant Protein | ||
IDO1-1419H | Recombinant Human IDO1 Protein (1-403 aa), His-tagged | +Inquiry |
IDO1-01H | Recombinant Human IDO1 Protein, His/Avi-tagged | +Inquiry |
IDO1-085H | Recombinant Human IDO1 Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
IDO1-2077M | Recombinant Mouse IDO1 Protein (1-407 aa), His-tagged | +Inquiry |
IDO1-4414M | Recombinant Mouse IDO1 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
IDO1-5300HCL | Recombinant Human IDO1 293 Cell Lysate | +Inquiry |
◆ Assay kits | ||
Kit-1782 | Mouse IDO1 Inhibitor Screening Assay Kit | +Inquiry |
Kit-1756 | Human IDO1 Fluorogenic Inhibitor Screening Assay Kit (384) | +Inquiry |
Kit-1758 | Human IDO1 Inhibitor Screening Assay Kit (384) | +Inquiry |
Kit-1754 | Human IDO1 Cell-Based Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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