Active Recombinant Human INS Protein
Cat.No. : | INS-53H |
Product Overview : | Recombinant Human Insulin is a two chain polypeptide containing 51 amino acids and has a MW = 5.8 kDa |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes insulin, a peptide hormone that plays a vital role in the regulation of carbohydrate and lipid metabolism. After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified, including insulin-dependent diabetes mellitus, permanent neonatal diabetes diabetes mellitus, maturity-onset diabetes of the young type 10 and hyperproinsulinemia. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. |
Source : | Yeast |
Species : | Human |
Bio-activity : | 29 units/mg |
Molecular Mass : | 5.8 kDa |
Endotoxin : | < 1EU/mg |
Purity : | >99.0% as determined by SEC-HPLC and SDS-PAGE. |
Storage : | Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | Centrifuge vial prior to opening. Add sterile 0.01 N HCL to the vial to fully solubilize the protein to a concentration not less than 1 mg/ml, to be further diluted to the working concentration. |
Gene Name : | INS insulin [ Homo sapiens (human) ] |
Official Symbol : | INS |
Synonyms : | IDDM; ILPR; IRDN; IDDM1; IDDM2; PNDM4; MODY10 |
Gene ID : | 3630 |
mRNA Refseq : | NM_000207.3 |
Protein Refseq : | NP_000198.1 |
MIM : | 176730 |
UniProt ID : | P01308 |
Products Types
◆ Recombinant Protein | ||
INS-14H | Active Recombinant Human Insulin, Low Endotoxin, Media Grade | +Inquiry |
INS-1187H | Recombinant Human INS Protein, His (Fc)-Avi-tagged | +Inquiry |
INS-5100H | Recombinant Human INS Protein, GST-tagged | +Inquiry |
INS-321 | Synthesis Human Proinsulin C-Peptide (55-89), bioactive peptide hormone | +Inquiry |
INS-2689C | Recombinant Chicken INS Protein, His-tagged | +Inquiry |
◆ Native Protein | ||
INS-5435B | Native Bovine Insulin | +Inquiry |
INS-512D | Native Bovine INS | +Inquiry |
◆ Lysates | ||
INS-5195HCL | Recombinant Human INS 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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