Active Recombinant Human NCR2 Protein, Fc Chimera

• Cat.No.: NCR2-1096H
• Product Overview: Recombinant Human NCR2 (Accession # O95944), fused with , was produced in Mouse myeloma cell line, NS0-derived.

Specification

• Source: Mammalian cells
• Species: Human
• Tag: Fc
• Predicted N Terminal: No results obtained: Gln22 predicted
• Form: Lyophilized from a 0.2 µm filtered solution in PBS.
• Bio-activity: Measured by its ability to bind HeLa human cervical epithelial carcinoma cells in a flow cytometry assay.When 400 ng of rhNKp44 Fc chimera is added to 2 x 10^5 Hela cells, >25% cells bind to the protein.
• Molecular Mass: Recombinant Human NCR2, Fc Chimera has a calculated MW of 45 kDa (monomer). In SDS-PAGE migrates as 61-67 kDa, reducing conditions.
• Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).

Gene Information

• Gene Name: NCR2 natural cytotoxicity triggering receptor 2 [ Homo sapiens ]
• Official Symbol: NCR2
• Synonyms: NCR2; natural cytotoxicity triggering receptor 2; LY95, lymphocyte antigen 95 (activating NK receptor; NK p44); CD336; NK p44; NK cell-activating receptor; NK cell activating receptor (NKp44); natural killer cell p44-related protein; lymphocyte antigen 95 (activating NK-receptor; NK-p44); lymphocyte antigen 95 homolog (activating NK-receptor; LY95; NKP44; NK-p44; dJ149M18.1
• Gene ID: 9436
• mRNA Refseq: NM_001199509
• Protein Refseq: NP_001186438
• MIM: 604531
• UniProt ID: O95944
• Chromosome Location: 6p21.1

Reviews

01/27/2023

The NCR2 proteins purchased from your company is suitable for ELISA.

08/12/2022

The technical expert communicated with me in time to understand the progress of my experiment and gave me suggestions for improvement.

07/20/2022

The high quality of the purchased protein helped me to obtain satisfactory experimental results.

Q&As

Where NCR2 is expressed?

NCR2 is only expressed on the surface of activated natural killer (NK) cells.

What is the relationship between NCR2 and DAP12?

NCR2 interacts with DAP12.

What function does NCR2 have?

NCR2 proteins function as cytotoxic activation receptors that enhance the efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.