Active Recombinant Human RSPO3 protein, His-tagged
Cat.No. : | RSPO3-3883H |
Product Overview : | Recombinant Human RSPO3 protein (Met 1-Val 146) was fused to His-tag at C-terminus and expressed in human 293 cells (HEK293). |
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Source : | HEK293 |
Species : | Human |
Tag : | His |
Form : | Lyophilized from sterile PBS, pH 7.4 |
Bio-activity : | Measured by its binding ability in a functional ELISA. Immobilized Human RSPO3 His at 2 μg/ml (100 μl/well) can bind Human RNF43 hFc, the EC50 of Human RNF43 hFc is 3.0-12.0 ng/mL. |
Molecular Mass : | The recombinant human RSPO3 consists of 136 amino acids and predictes a molecular mass of 15.3 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh RSPO3 is approximately 22-27 kDa due to different glycosylation. |
Protein Length : | Met 1-Val 146 |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method |
Purity : | > 96 % as determined by SDS-PAGE |
Storage : | Samples are stable for up to twelve months from date of receipt at -20°C to -80°C Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | RSPO3 R-spondin 3 [ Homo sapiens ] |
Official Symbol : | RSPO3 |
Synonyms : | RSPO3; R-spondin 3; R spondin 3 homolog (Xenopus laevis) , thrombospondin, type I, domain containing 2 , THSD2; R-spondin-3; FLJ14440; R-spondin 3 homolog; roof plate-specific spondin-3; protein with TSP type-1 repeat; thrombospondin, type I, domain containing 2; thrombospondin type-1 domain-containing protein 2; PWTSR; THSD2; CRISTIN1; |
Gene ID : | 84870 |
mRNA Refseq : | NM_032784 |
Protein Refseq : | NP_116173 |
MIM : | 610574 |
UniProt ID : | Q9BXY4 |
Products Types
◆ Recombinant Protein | ||
RSPO3-423H | Recombinant Human RSPO3 Protein, His-tagged | +Inquiry |
RSPO3-35H | Recombinant Human RSPO3 Protein | +Inquiry |
RSPO3-14554M | Active Recombinant Mouse RSPO3 Protein | +Inquiry |
RSPO3-2315Z | Recombinant Zebrafish RSPO3 | +Inquiry |
RSPO3-442H | Active Recombinant Human RSPO3 Protein | +Inquiry |
◆ Lysates | ||
RSPO3-1906HCL | Recombinant Human RSPO3 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionGenetic mutations in RSPO3 can disrupt normal development and tissue regeneration.
Targeting RSPO3 could offer advances in regenerative medicine and cancer therapy by modulating Wnt signaling.
RSPO3 plays a significant role in maintaining stem cell populations and influencing their differentiation.
It stimulates tissue development and regeneration by activating Wnt pathways, essential for cellular proliferation.
RSPO3, a member of the R-spondin family, enhances Wnt signaling, crucial for cellular growth and differentiation.
Altered RSPO3 activity is linked to cancer development and progression, particularly in colorectal cancer.
RSPO3 interacts synergistically with Wnt pathway components, amplifying signal transduction.
Customer Reviews (3)
Write a reviewDependable partner, a vital research collaborator.
Consistency in quality, invaluable for our experiments.
Reliable data source, accelerates our research progress.
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