Active Recombinant Human SLAMF8, Fc-tagged
Cat.No. : | SLAMF8-690H |
Product Overview : | The recombinant human SLAMF8-Fc fusion protein is expressed as a 440-amino acid protein consisting of Ala23 - Val234 region of SLAMF8 (UniProt accession #Q9P0V8) and a C-terminal Fc from human IgG1, which exists as a dimer under non-reducing conditions. |
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Source : | Human cells |
Species : | Human |
Tag : | Fc |
Form : | Supplied at 0.5 mg/ml in sterile PBS pH7.4 (carrier & preservative free). |
Bio-activity : | Immobilized SLAMF8 interacts homophilically with SLAMF8 in a functional ELISA |
Molecular Mass : | Calculated molecular mass (kDa): 49.1; Estimated by SDS-PAGE under reducing condition (kDa): 65-75 |
AA Sequence : | AQVLSKVGGSVLLVAARPPGFQVRE AIWRSLWPSEELLATFFRGSLETLY HSRFLGRAQLHSNLSLELGPLESG DSGNFSVLMVDTRGQPWTQTLQLKV YDAVPRPVVQVFIAVERDAQPSKTC QVFLSCWAPNISEITYSWRRETTM DFGMEPHSLFTDGQVLSISLGPGDR DVAYSCIVSNPVSWDLATVTPWDSC HHEAAPGKASYKDVSTGTHTCPPC PAPELLGGPSVFLFPPKPKDTLMIS RTPEVTCVVVDVSHEDPEVKFNWYV DGVEVHNAKTKPREEQYNSTYRVV SVLTVLHQDWLNGKEYKCKVSNKAL PAPIEKTISKAKGQPREPQVYTLPP SREEMTKNQVSLTCLVKGFYPSDI AVEWESNGQPENNYKTTPPVLDSDG SFFLYSKLTVDKSRWQQGNVFSCSV MHEALHNHYTQKSLSLSPGK |
Endotoxin : | <0.1 eu per 1 μg of purified recombinant protein determined by the lal>0.1> |
Purity : | >95% judged by SDS-PAGE under reducing condition |
Storage : | The product is shipped at 4°C. Upon receipt, centrifuge the product briefly before opening the vial. It is recommended to store small aliquots at the temperature below –20°C for long-term storage and the product is stable for 3 months. The undiluted protein can be stored at 4°C for no more than 2 weeks. Avoid repeated freeze-thaw cycles. |
Gene Name : | SLAMF8 SLAM family member 8 [ Homo sapiens ] |
Official Symbol : | SLAMF8 |
Synonyms : | SLAMF8; SLAM family member 8; BLAME; CD353; SBBI42; BCM-like membrane protein; B lymphocyte activator macrophage expressed; B-lymphocyte activator macrophage expressed; FLJ20442; MGC129578; |
Gene ID : | 56833 |
mRNA Refseq : | NM_020125 |
Protein Refseq : | NP_064510 |
MIM : | 606620 |
UniProt ID : | Q9P0V8 |
Chromosome Location : | 1q23.1 |
Function : | receptor activity; |
Products Types
◆ Recombinant Protein | ||
Slamf8-4063M | Recombinant Mouse Slamf8 protein(Met1-Asp231), His-tagged | +Inquiry |
SLAMF8-4063H | Recombinant Human SLAMF8 Protein, His (Fc)-Avi-tagged | +Inquiry |
SLAMF8-726H | Recombinant Human SLAMF8 Protein, His-tagged | +Inquiry |
SLAMF8-120H | Recombinant Human SLAMF8 Protein, C-His-tagged | +Inquiry |
Slamf8-5899M | Recombinant Mouse Slamf8 Protein, Myc/DDK-tagged | +Inquiry |
◆ Lysates | ||
SLAMF8-2093MCL | Recombinant Mouse SLAMF8 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionDysregulation of SLAMF8 can contribute to inflammatory and autoimmune diseases.
Therapeutic interventions could potentially target SLAMF8 to modulate immune responses in various diseases.
It acts as an inhibitory receptor, modulating immune cell activation and cytokine production.
SLAMF8 activity is governed by interactions with other cell surface receptors and intracellular signaling pathways.
SLAMF8 is predominantly found in myeloid cells, like macrophages and dendritic cells.
SLAMF8 regulates immune responses, particularly in myeloid cells.
It participates in cell-cell signaling, influencing immune cell activation and function.
Customer Reviews (3)
Write a reviewPerfect for biological assays.
Product works as expected.
Very reliable, worth the price.
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