Active Recombinant Rat Robo1 Protein, Fc Chimera

• Cat.No.: Robo1-988R
• Product Overview: Recombinant Rat Robo1 (Accession # O55005), fused with , was produced in Mouse myeloma cell line, NS0-derived.

Specification

• Source: Mammalian cells
• Species: Rat
• Tag: Fc
• Predicted N Terminal: Lys19
• Form: Lyophilized from a 0.2 µm filtered solution in PBS.
• Bio-activity: Measured by its binding ability in a functional ELISA.Biotinylated recombinant mouse Slit-3 immobilized on a streptavidin-coated plate at 1 µg/mL can bind Recombinant Rat ROBO1 Fc Chimera with an apparent Kd <10 nM.
• Molecular Mass: Recombinant Rat Robo1, Fc Chimera has a calculated MW of 86.2 kDa (monomer). In SDS-PAGE migrates as 110-115 kDa, reducing conditions.
• Purity: >95%, by SDS-PAGE under reducing conditions and visualized by silver stain.
• Storage: Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC).
• Reconstitution: Reconstitute at 50 µg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.

Gene Information

• Gene Name: Robo1 roundabout homolog 1 (Drosophila) [ Rattus norvegicus ]
• Official Symbol: Robo1
• Synonyms: ROBO1; roundabout homolog 1 (Drosophila); roundabout homolog 1
• Gene ID: 58946
• mRNA Refseq: NM_022188
• Protein Refseq: NP_071524

Reviews

06/28/2023

ROBO1 is able to maintain its biological activity and structural integrity under specific experimental conditions.

06/07/2022

ROBO1 products have low endotoxin levels and do not interfere with experimental results.

07/31/2021

When using ROBO1 for experiments, you can get a clear and reliable interpretation of your results.

Q&As

What is the association between ROBO1 recombinant protein and tumors?

Some studies have shown that ROBO1 recombinant protein may be involved in the initiation and progression of tumors, especially in neurological tumors.

Does ROBO1 recombinant protein function in pregnant women?

The level of ROBO1 recombinant protein in pregnant women may change due to the needs of fetal growth and development, and regular monitoring is required.

Does ROBO1 have a function in the human body?

ROBO1 is mainly involved in axon guidance and neural network formation in the human body, affecting the development and function of the nervous system.

If the level of ROBO1 recombinant protein is abnormal, what should I do?

If the level of ROBO1 recombinant protein is abnormal, treatment may include the use of drugs or other special treatments, depending on the condition and the doctor's recommendation.

Is there a treatment for ROBO1 recombinant proteins?

The current treatments for ROBO1 recombinant protein mainly include gene therapy, protein replacement therapy, and drug therapy for axon guidance.

What is the association between ROBO1 recombinant protein and neurological diseases?

ROBO1 recombinant protein may be involved in the occurrence and progression of neurological diseases, especially in glioma, neural tube defects, and autism.