Recombinant Human ACADM, His-tagged
Cat.No. : | ACADM-26047TH |
Product Overview : | Recombinant Human full length ACADM with a N terminal His tag; a single, non-glycosylated polypeptide chain; 417 amino acids with tag; predicted Mwt: 45.9 kDa. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes the medium-chain specific (C4 to C12 straight chain) acyl-Coenzyme A dehydrogenase. The homotetramer enzyme catalyzes the initial step of the mitochondrial fatty acid beta-oxidation pathway. Defects in this gene cause medium-chain acyl-CoA dehydrogenase deficiency, a disease characterized by hepatic dysfunction, fasting hypoglycemia, and encephalopathy, which can result in infantile death. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Protein length : | 396 amino acids |
Conjugation : | HIS |
Molecular Weight : | 45.900kDa |
Source : | E. coli |
Form : | Liquid |
Purity : | >90% by SDS-PAGE |
Storage buffer : | pH: 7.50Constituents:20% Glycerol, 0.32% Tris HCl |
Storage : | Please see Notes section |
Sequences of amino acids : | MGSSHHHHHH SSGLVPRGSH MKANRQREPG LGFSFEFTEQ QKEFQATARK FAREEIIPVA AEYDKTGEYP VPLIRRAWEL GLMNTHIPEN CGGLGLGTFD ACLISEELAY GCTGVQTAIE GNSLGQMPII IAGNDQQKKK YLGRMTEEPL MCAYCVTEPG AGSDVAGIKT KAEKKGDEYI INGQKMWITN GGKANWYFLL ARSDPDPKAP ANKAFTGFIV EADTPGIQIG RKELNMGQRC SDTRGIVFED VKVPKENVLI GDGAGFKVAM GAFDKTRPVV AAGAVGLAQR ALDEATKYAL ERKTFGKLLV EHQAISFMLA EMAMKVELAR MSYQRAAWEV DSGRRNTYYA SIAKAFAGDI ANQLATDAVQ ILGGNGFNTE YPVEKLMRDA KIYQIYEGTS QIQRLIVARE HIDKYKN |
Sequence Similarities : | Belongs to the acyl-CoA dehydrogenase family. |
Gene Name : | ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain [ Homo sapiens ] |
Official Symbol : | ACADM |
Synonyms : | ACADM; acyl-CoA dehydrogenase, C-4 to C-12 straight chain; acyl Coenzyme A dehydrogenase, C 4 to C 12 straight chain; medium-chain specific acyl-CoA dehydrogenase, mitochondrial; ACAD1; MCAD; MCADH; |
Gene ID : | 34 |
mRNA Refseq : | NM_000016 |
Protein Refseq : | NP_000007 |
MIM : | 607008 |
Uniprot ID : | P11310 |
Chromosome Location : | 1p31 |
Pathway : | Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA, organism-specific biosystem; Beta oxidation of octanoyl-CoA to hexanoyl-CoA, organism-specific biosystem; FOXA2 and FOXA3 transcription factor networks, organism-specific biosystem; Fatty Acid Beta Oxidation, organism-specific biosystem; Fatty acid metabolism, organism-specific biosystem; |
Function : | acryloyl-CoA reductase activity; acyl-CoA dehydrogenase activity; acyl-CoA dehydrogenase activity; acyl-CoA dehydrogenase activity; acyl-CoA dehydrogenase activity; |
Products Types
◆ Recombinant Protein | ||
Acadm-503M | Recombinant Mouse Acadm Protein, MYC/DDK-tagged | +Inquiry |
ACADM-238M | Recombinant Mouse ACADM Protein, His (Fc)-Avi-tagged | +Inquiry |
ACADM-23H | Recombinant Human ACADM Protein, His-tagged | +Inquiry |
Acadm-8157M | Recombinant Mouse Acadm protein, His & T7-tagged | +Inquiry |
ACADM-134H | Recombinant Human ACADM Protein, GST-Tagged | +Inquiry |
◆ Lysates | ||
ACADM-9114HCL | Recombinant Human ACADM 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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