Recombinant Cynomolgus IL17A protein, His-Avi-tagged

• Cat.No.: IL17A-056C
• Product Overview: Recombinant Cynomolgus IL17A Protein is expressed from mammalian with a His and avi Tag at the C-terminal. It contains Gly24-Ala155.

Specification

• Description: Interleukin‑17A (IL‑17A), also known as CTLA‑8, is a 15‑20 kDa glycosylated cytokine that plays an important role in anti‑microbial and chronic inflammation. The six IL‑17 cytokines (IL‑17A‑F) are encoded by separate genes but adopt a conserved cystine knot fold. IL-17A is a ligand for IL17RA and IL17RC. The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC. Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines.
• Source: HEK293
• Species: Cynomolgus
• Tag: His-Avi
• Form: Supplied as 0. 22um filtered solution in PBS (pH 7. 4).
• Molecular Mass: The Cynomolgus IL17A Protein has a calculated MW of 18. 2kDa. As a result of glycosylation, the protein migrates as 26-32kDa based on Bis-Tris PAGE.
• Protein length: It contains Gly24-Ala155.
• Endotoxin: Less than 0. 1EU per ug by the LAL method.
• Purity: > 95% as determined by Bis-Tris PAGE
• Storage: The product should be stored at -70°C. Please do not repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents.

Gene Information

• Gene Name: IL17A interleukin 17A [ Macaca fascicularis (crab-eating macaque) ]
• Official Symbol: IL17A
• Synonyms: CTLA-8; CTLA8cytotoxic T-lymphocyte-associated serine esterase 8; Cytotoxic T-lymphocyte-associated antigen 8; IL17; IL-17; IL17A; IL-17A; IL-17Acytotoxic T-lymphocyte-associated protein 8; IL-17CTLA-8; IL17interleukin-17A; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8); interleukin 17A
• Gene ID: 102119976
• mRNA Refseq: XM_005552759. 2
• Protein Refseq: XP_005552816. 1