Recombinant Equine Interleukin 13
Cat.No. : | IL13-252E |
Product Overview : | Recombinant Equine IL-13 was expressed inYeast. MW= 12.6 kDa (115 aa). |
- Specification
- Gene Information
- Related Products
Cat. No. : | IL13-252E |
Description : | IL13 is an immunoregulatory cytokine produced primarily by activated Th2 cells. IL-13 is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils. This gene, IL3, IL5, IL4, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL4. |
Source : | Yeast. |
Formulation/ Reconstitution : | Lyophilized. Reconstitute with sterile phosphate-buffered saline containing at least 0.1% carrier protein. |
Purification : | Ion-exchange chromatography. |
Purity : | >95% as visualized by SDS-PAGE analysis. |
Amino Acid Sequence : | SPAPLPSSMA LKELIKELVN ITQNQAPLCN GSMVWSVNLT ADTYCRALES LSNVSTCSAI QNTRKMLTKL CPHQLSAGQV SSERARDTKI EVIVLVKDLL KNLRKIFHGG KHVDA. |
Bioactivity : | In testing. |
Stability And Storage : | Stable for up to twelve months from date of receipt at -20°C. Stable for at least 3 months when stored in working aliquots with a carrier protein at -20°C. Avoid repeated freeze/thaw cycles. |
Gene Name : | IL-13 interleukin-13 [ Equus caballus ] |
Synonyms : | interleukin-13; IL-13 |
Gene ID : | 100034113 |
mRNA Refseq : | NM_001143791.1 |
Protein Refseq : | NP_001137263.1 |
Chromosome Location : | 14 |
Pathway : | Asthma; Cytokine-cytokine receptor interaction; Fc epsilon RI signaling pathway; Jak-STAT signaling pathway |
Products Types
◆ Recombinant Protein | ||
IL13-1660R | Recombinant Rhesus monkey IL13 Protein, His-tagged | +Inquiry |
Il13-49M | Active Recombinant Mouse Il13 Protein (Pro22-Fhe131), C-His tagged, Animal-free, Carrier-free | +Inquiry |
Il13-090M | Active Recombinant Mouse Il13 Protein | +Inquiry |
IL13-4328Z | Recombinant Zebrafish IL13 Protein | +Inquiry |
IL13-143H | Recombinant Active Human IL13 Protein, His-tagged(C-ter) | +Inquiry |
◆ Lysates | ||
IL13-2922HCL | Recombinant Human IL13 cell lysate | +Inquiry |
IL13-1894CCL | Recombinant Cynomolgus IL13 cell lysate | +Inquiry |
IL13-1336MCL | Recombinant Mouse IL13 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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