Recombinant Full Length Human ALS2CR8 Protein, GST-tagged
Cat.No. : | ALS2CR8-1303HF |
Product Overview : | Human ALS2CR8 full-length ORF ( NP_079020.12, 1 a.a. - 718 a.a.) recombinant protein with GST-tag at N-terminal. |
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Description : | CARF (Calcium Responsive Transcription Factor) is a Protein Coding gene. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding. |
Source : | In Vitro Cell Free System |
Species : | Human |
Tag : | GST |
Molecular Mass : | 106.2 kDa |
Protein Length : | 718 amino acids |
AA Sequence : | MEQSNDSLRV NHNDGEESKT SAQVFEHLIC MDSRDSSFGQ NDSPTVLPIT TREANNSLIS QNIPGPLTQT QTLSAEQFHL VDQNGQAIQY ELQSLGESNA QMMIVASPTE NGQVLRVIPP TQTGMAQVII PQGQLVDVNS PRDVPEEKPS NRNLPTVRVD TLADNTSNYI LHPQTSFPLP KKSVTGMLEE PLLGPLQPLS SNTPIWACRL RSCEKIGDSY RGYCVSETEL ESVLTFHKQQ TQSVWGTRQS PSPAKPATRL MWKSQYVPYD GIPFVNAGSR AVVMECQYGP RRKGFQLKKV SEQESRSCQL YKATCPARIY IKKVQKFPEY RVPTDPKIDK KIIRMEQEKA FNMLKKNLVD AGGVLRWYVQ LPTQQAHQYH ELETPCLTLS PSPFPVSSLE EEETAVRDEN CALPSRLHPQ VAHKIQELVS QGIEQVYAVR KQLRKFVERE LFKPDEVPER HNLSFFPTVN DIKNHIHEVQ KSLRNGDTVY NSEIIPATLQ WTTDSGNILK ETMTVTFAEG NSPGESITTK VETNQTRGSL SPEPTHLLSS LSSFQPKIFT QLQGLQLQPR YTSPDESPAV VSVNNQPSSS PSGLLDTIGS AVMNNNSLLL GQSHSLQRDT CLTQNNSTAS TMGNLPEPDQ NLVAMDELVE VGDVEDTGNL EGTVHRILLG DVQTIPIQII DNHSALIEEN PESTISVSQV KQEPKEPALS MEAKNCGL |
Applications : | Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | ALS2CR8 amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 8 [ Homo sapiens ] |
Official Symbol : | ALS2CR8 |
Synonyms : | ALS2CR8; amyotrophic lateral sclerosis 2 (juvenile) chromosome region, candidate 8; amyotrophic lateral sclerosis 2 chromosomal region candidate gene 8 protein; calcium response factor; CaRF; FLJ21579; NYD SP24; calcium-response factor; testis development protein NYD-SP24; CARF; NYD-SP24; FLJ12675; DKFZp667N246 |
Gene ID : | 79800 |
mRNA Refseq : | NM_001104586 |
Protein Refseq : | NP_001098056 |
MIM : | 607586 |
UniProt ID : | Q8N187 |
Products Types
◆ Recombinant Protein | ||
ALS2CR8-300R | Recombinant Rat ALS2CR8 Protein, His (Fc)-Avi-tagged | +Inquiry |
ALS2CR8-9603H | Recombinant Human ALS2CR8, GST-tagged | +Inquiry |
ALS2CR8-644R | Recombinant Rat ALS2CR8 Protein | +Inquiry |
ALS2CR8-509H | Recombinant Human ALS2CR8 protein, GST-tagged | +Inquiry |
◆ Lysates | ||
ALS2CR8-68HCL | Recombinant Human ALS2CR8 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionThe enzymatic activities of ALS2CR8 are not well-characterized, and further studies are needed to identify its potential substrates or targets.
ALS2CR8 undergoes specific post-translational modifications, including phosphorylation or ubiquitination, that regulate its activity, stability, or subcellular localization.
ALS2CR8 plays a role in synaptic function, affecting processes such as neurotransmitter release, postsynaptic receptor trafficking, or synaptic vesicle dynamics.
Targeting ALS2CR8 or its associated pathways may hold therapeutic potential for treating neurological disorders, aiming to modulate synaptic function, promote neuronal survival, or enhance neuronal connectivity.
ALS2CR8 is implicated in intracellular signaling pathways, such as those involved in neuronal survival, synaptic plasticity, or gene expression regulation.
ALS2CR8 expression is dynamically regulated during neuronal development and can be influenced by factors such as neuronal activity, neurotrophic factors, or signaling molecules.
ALS2CR8 is crucial for neuronal development and function, potentially influencing processes such as neurite outgrowth, synaptogenesis, or synaptic transmission through various molecular mechanisms.
ALS2CR8 interacts with specific proteins or molecular complexes involved in neuronal signaling, cytoskeletal organization, or intracellular transport, which contribute to its cellular functions.
ALS2CR8 is primarily localized to the cytoplasm, with potential associations with specific cellular compartments involved in neuronal function.
ALS2CR8 contains functional domains and motifs, such as protein-protein interaction domains or enzymatic domains, that play a role in its molecular functions.
Customer Reviews (3)
Write a reviewCompatible with automated liquid handling systems.
Accurate assessment of protein expression changes.
Low interference from endogenous proteins in samples.
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