Recombinant Full Length Human ASB6 Protein, GST-tagged

• Cat.No.: ASB6-1359HF
• Product Overview: Human ASB6 full-length ORF ( AAH01719, 1 a.a. - 197 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The protein encoded by this gene belongs to a family of ankyrin repeat proteins that, along with four other protein families, contain a C-terminal SOCS box motif. Growing evidence suggests that the SOCS box, similar to the F-box, acts as a bridge between specific substrate-binding domains and the more generic proteins that comprise a large family of E3 ubiquitin protein ligases. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jan 2011]
• Source: In Vitro Cell Free System
• Species: Human
• Tag: GST
• Molecular Mass: 47.41 kDa
• Protein Length: 197 amino acids
• AA Sequence: MPFLHGFRRI IFEYQPLVDA IPGSLGIQDP ERQESLDRPS YVASEESRIL VLTELLERKA HSPFYQEGVS NALLKMAELG LTRAADVLLR HGANLNFEDP VTYYTALHIA VLRNQPDMVE LLVHHGADVN RRDREKLLCS MLWPAATGCR STILRTFVSY WKEGQTSRPP PKMGTQCSPA SSSCLVRPWE GTKRRPR
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCl, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ASB6 ankyrin repeat and SOCS box containing 6 [ Homo sapiens ]
• Official Symbol: ASB6
• Synonyms: ASB6; ankyrin repeat and SOCS box containing 6; ankyrin repeat and SOCS box protein 6; ankyrin repeat and SOCS box-containing 6; MGC1024; FLJ20548
• Gene ID: 140459
• mRNA Refseq: NM_001202403
• Protein Refseq: NP_001189332
• MIM: 615051
• UniProt ID: Q9NWX5

Reviews

04/08/2021

Its high specificity and robust activity make it an ideal candidate for investigating intricate molecular interactions and elucidating complex biological mechanisms.

07/08/2019

This variety allows me to select the most appropriate option based on the specific requirements of my research.

07/17/2018

With its remarkable quality, reliability, and the manufacturer's excellent technical support, I am confident that it will be an invaluable asset in driving my scientific inquiries forward and facilitating groundbreaking discoveries in my field.

Q&As

Are there any known molecular interactions involving ASB6?

The molecular interactions involving ASB6 are not well-characterized. Identifying its binding partners or protein substrates would provide insights into its functional mechanisms.

Are there any known upstream regulators that can modulate ASB6 expression?

The specific upstream regulators that modulate ASB6 expression have not been extensively investigated. Further studies are needed to identify the regulatory mechanisms involved.

Can ASB6 be used as a diagnostic marker for any diseases or conditions?

Currently, ASB6 has not been identified as a diagnostic marker for any specific diseases or conditions. Further investigations may reveal its potential diagnostic applicability.

Is there any evidence to suggest a role for ASB6 in cancer development?

There is limited research on the role of ASB6 in cancer development. While some studies have suggested a possible involvement of ASB6 in certain types of cancer, additional research is required to establish a definitive link.