Recombinant Full Length Human DDX4 Protein, C-Flag-tagged
Cat.No. : | DDX4-500HFL |
Product Overview : | Recombinant Full Length Human DDX4 Protein, fused to Flag-tag at C-terminus, was expressed in Mammalian cells. |
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Description : | DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a homolog of VASA proteins in Drosophila and several other species. The gene is specifically expressed in the germ cell lineage in both sexes and functions in germ cell development. Multiple transcript variants encoding different isoforms have been found for this gene. |
Source : | Mammalian cells |
Species : | Human |
Tag : | Flag |
Form : | 25 mM Tris HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 79.1 kDa |
AA Sequence : | MGDEDWEAEINPHMSSYVPIFEKDR YSGENGDNFNRTPASSSEMDDGPSR RDHFMKSGFASGRNFGNRDA GECNKRDNTSTMGGFGVGKSFGNRG FSNSRFEDGDSSGFWRESSNDCEDN PTRNRGFSKRGGYRDGNNSE ASGPYRRGGRGSFRGCRGGFGLGSP NNDLDPDECMQRTGGLFGSRRPVLS GTGNGDTSQSRSGSGSERGG YKGLNEEVITGSGKNSWKSEAEGGE SSDTQGPKVTYIPPPPPEDEDSIFA HYQTGINFDKYDTILVEVSG HDAPPAILTFEEANLCQTLNNNIAK AGYTKLTPVQKYSIPIILAGRDLMA CAQTGSGKTAAFLLPILAHM MHDGITASRFKELQEPECIIVAPTR ELVNQIYLEARKFSFGTCVRAVVIY GGTQLGHSIRQIVQGCNILC ATPGRLMDIIGKEKIGLKQIKYLVL DEADRMLDMGFGPEMKKLISCPGMP SKEQRQTLMFSATFPEEIQR LAAEFLKSNYLFVAVGQVGGACRDV QQTVLQVGQFSKREKLVEILRNIGD ERTMVFVETKKKADFIATFL CQEKISTTSIHGDREQREREQALGD FRFGKCPVLVATSVAARGLDIENVQ HVINFDLPSTIDEYVHRIGR TGRCGNTGRAISFFDLESDNHLAQP LVKVLTDAQQDVPAWLEEIAFSTYI PGFSGSTRGNVFASVDTRKG KSTLNTAGFSSSQAPNPVDDESWDT RTRPLEQKLISEEDLAANDILDYKD DDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining. |
Stability : | Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : | Store at -80 centigrade. |
Concentration : | >50 ug/mL as determined by microplate BCA method. |
Preparation : | Recombinant protein was captured through anti-DDK affinity column followed by conventional chromatography steps. |
Gene Name : | DDX4 DEAD-box helicase 4 [ Homo sapiens (human) ] |
Official Symbol : | DDX4 |
Synonyms : | VASA |
Gene ID : | 54514 |
mRNA Refseq : | NM_024415.3 |
Protein Refseq : | NP_077726.1 |
MIM : | 605281 |
UniProt ID : | Q9NQI0 |
Products Types
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◆ Lysates | ||
DDX4-7006HCL | Recombinant Human DDX4 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionDDX4 protein expression is used as a biomarker for germ cell development and certain reproductive diseases, aiding in diagnosis and prognosis.
Yes, DDX4 protein plays an essential role in the development of both male and female gametes, making it a crucial factor in reproductive health.
DDX4 protein is involved in the regulation of oocyte and embryo development, and its dysregulation can impact fertility and reproductive outcomes.
DDX4 protein expression can be assessed using immunohistochemistry, western blotting, and other molecular techniques in clinical settings.
Yes, genetic mutations in DDX4 protein have been linked to certain forms of infertility and germ cell tumors.
Customer Reviews (3)
Write a reviewTheir prompt assistance and willingness to go above and beyond to ensure my success have been immensely valuable.
This protein has proven to be an invaluable asset in my experiments, enabling accurate and precise measurements with exceptional sensitivity.
Its purity, stability, and consistency are unparalleled, ensuring reliable and reproducible results in my research.
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