Recombinant Human ACAA2, His-tagged
Cat.No. : | ACAA2-3044H |
Product Overview : | ACAA2 |
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Description : | The encoded protein catalyzes the last step of the mitochondrial fatty acid beta-oxidation spiral. Unlike most mitochondrial matrix proteins, it contains a non-cleavable amino-terminal targeting signal. [provided by RefSeq, Jul 2008] |
Source : | E. Coli |
Species : | Human |
Tag : | His |
Form : | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol,1mM DTT |
Molecular Mass : | 42.6 kDa (404aa) confirmed by MALDI-TOF |
Protein length : | 397 |
Purity : | >85% by SDS - PAGE |
Applications : | SDS-PAGE |
Notes : | Small volumes of ACAA2 recombinant protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice. |
Storage : | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
Warning : | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Gene Name : | ACAA2 acetyl-CoA acyltransferase 2 [ Homo sapiens ] |
Official Symbol : | ACAA2 |
Synonyms : | ACAA2; acetyl-CoA acyltransferase 2; acetyl Coenzyme A acyltransferase 2; 3-ketoacyl-CoA thiolase, mitochondrial; DSAEC; mitochondrial 3 oxoacyl Coenzyme A thiolase; T1; beta ketothiolase; beta-ketothiolase; acetyl-Coenzyme A acyltransferase 2; mitochondrial 3-oxoacyl-CoA thiolase; mitochondrial 3-oxoacyl-Coenzyme A thiolase; FLJ35992; FLJ95265; |
Gene ID : | 10449 |
mRNA Refseq : | NM_006111 |
Protein Refseq : | NP_006102 |
MIM : | 604770 |
UniProt ID : | P42765 |
Chromosome Location : | 18q21 |
Pathway : | Fatty Acid Biosynthesis, organism-specific biosystem; Fatty acid biosynthesis, elongation, mitochondria, organism-specific biosystem; Fatty acid biosynthesis, elongation, mitochondria, conserved biosystem; Fatty acid elongation, organism-specific biosyste |
Function : | acetyl-CoA C-acyltransferase activity; protein binding; transferase activity, transferring acyl groups other than amino-acyl groups; |
Products Types
◆ Recombinant Protein | ||
ACAA2-89R | Recombinant Rat ACAA2 Protein, His (Fc)-Avi-tagged | +Inquiry |
ACAA2-252H | Recombinant Human ACAA2 Protein, His (Fc)-Avi-tagged | +Inquiry |
Acaa2-1484M | Recombinant Mouse Acaa2 Protein, Myc/DDK-tagged | +Inquiry |
ACAA2-25R | Recombinant Rhesus Macaque ACAA2 Protein, His (Fc)-Avi-tagged | +Inquiry |
ACAA2-1316H | Recombinant Human ACAA2 Protein (17-397 aa), His-tagged | +Inquiry |
◆ Lysates | ||
ACAA2-9118HCL | Recombinant Human ACAA2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionThe molecular weight of ACAA2 protein is approximately 45 kDa.
ACAA2 expression is upregulated in some types of cancer, including prostate and ovarian cancer.
ACAA2 protein is regulated at the transcriptional level by multiple factors, including PPARs and SREBP-1c.
ACAA2 is predominantly expressed in the liver and adipose tissue.
ACAA2 may have clinical significance in the diagnosis and treatment of metabolic disorders and certain types of cancer.
ACAA2 protein's primary function is to participate in fatty acid and ketone body metabolism.
ACAA2 has been implicated in the development of metabolic disorders, including obesity and type 2 diabetes.
Some known inhibitors of ACAA2 include hexachlorophene and fusicoccin-A, while known activators include medium-chain fatty acids and certain drugs.
ACAA2 catalyzes the transfer of acyl groups between CoA and acyl-CoA substrates.
The three-dimensional structure of ACAA2 protein is characterized by an alpha/beta hydrolase fold.
Customer Reviews (3)
Write a reviewHighly effective in detecting and measuring the activity of protein kinases in kinase assays.
Provides consistent and accurate quantification of the target protein in different assay formats.
Shows excellent performance in detecting and measuring the activity of proteases in protease assays.
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