Recombinant Human ACSS3 Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | ACSS3-2060H |
Product Overview : | ACSS3 MS Standard C13 and N15-labeled recombinant protein (NP_078836) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
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Description : | Catalyzes the synthesis of acetyl-CoA from short-chain fatty acids. Propionate is the preferred substrate. Can utilize acetate and butyrate with a much lower affinity. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 74.8 kDa |
AA Sequence : | MKPSWLQCRKVTSAGGLGGPLPGSS PARGAGAALRALVVPGPRGGLGGRG CRALSSGSGSEYKTHFAASVTDPER FWGKAAEQISWYKPWTKTLENKHSP STRWFVEGMLNICYNAVDRHIENGK GDKIAIIYDSPVTNTKATFTYKEVL EQVSKLAGVLVKHGIKKGDTVVIYM PMIPQAMYTMLACARIGAIHSLIFG GFASKELSSRIDHVKPKVVVTASFG IEPGRRVEYVPLVEEALKIGQHKPD KILIYNRPNMEAVPLAPGRDLDWDE EMAKAQSHDCVPVLSEHPLYILYTS GTTGLPKGVIRPTGGYAVMLHWSMS SIYGLQPGEVWWAASDLGWVVGHSY ICYGPLLHGNTTVLYEGKPVGTPDA GAYFRVLAEHGVAALFTAPTAIRAI RQQDPGAALGKQYSLTRFKTLFVAG ERCDVETLEWSKNVFRVPVLDHWWQ TETGSPITASCVGLGNSKTPPPGQA GKSVPGYNVMILDDNMQKLKARCLG NIVVKLPLPPGAFSGLWKNQEAFKH LYFEKFPGYYDTMDAGYMDEEGYLY VMSRVDDVINVAGHRISAGAIEESI LSHGTVADCAVVGKEDPLKGHVPLA LCVLRKDINATEEQVLEEIVKHVRQ NIGPVAAFRNAVFVKQLPKTRSGKI PRSALSAIVNGKPYKITSTIEDPSI FGHVEEMLKQATRTRPLEQKLISEE DLAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | ACSS3 acyl-CoA synthetase short-chain family member 3 [ Homo sapiens (human) ] |
Official Symbol : | ACSS3 |
Synonyms : | ACSS3; acyl-CoA synthetase short-chain family member 3; acyl-CoA synthetase short-chain family member 3, mitochondrial; FLJ21963; AMP-binding enzyme, 33217; |
Gene ID : | 79611 |
mRNA Refseq : | NM_024560 |
Protein Refseq : | NP_078836 |
MIM : | 614356 |
UniProt ID : | Q9H6R3 |
Products Types
◆ Recombinant Protein | ||
ACSS3-280M | Recombinant Mouse ACSS3 Protein, His (Fc)-Avi-tagged | +Inquiry |
ACSS3-265H | Recombinant Human ACSS3 Protein, His (Fc)-Avi-tagged | +Inquiry |
Acss3-1514M | Recombinant Mouse Acss3 Protein, Myc/DDK-tagged | +Inquiry |
ACSS3-18H | Recombinant Human ACSS3, His-tagged | +Inquiry |
ACSS3-1237M | Recombinant Mouse ACSS3 Protein | +Inquiry |
◆ Lysates | ||
ACSS3-9067HCL | Recombinant Human ACSS3 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionACSS3 has been found to be upregulated in certain cancers and is associated with tumor growth, progression, and metabolic reprogramming.
Yes, ACSS3 can influence gene expression through its role in protein acetylation, which can modify histones and transcription factors.
ACSS3 activity is sensitive to cellular energy levels, particularly levels of ATP (adenosine triphosphate), which is an indicator of energy availability.
ACSS3 expression can be regulated by various factors, including nutrient availability, cellular energy status, and transcriptional control.
Acetyl-CoA is involved in various metabolic processes, including the citric acid cycle (Krebs cycle), fatty acid synthesis, and protein acetylation.
Recent studies have linked dysregulation of ACSS3 to various diseases, including cancer, obesity, and metabolic disorders.
Yes, there are commercially available antibodies and kits that can be used for detecting ACSS3 protein in biological samples, such as Western blotting or immunohistochemistry.
Yes, ACSS3 protein can be produced using recombinant DNA technology by cloning the ACSS3 gene into an expression vector and expressing it in a suitable host organism, such as bacteria or yeast.
The activity of ACSS3 can be measured through enzymatic assays that assess the conversion of acetate to acetyl-CoA in vitro, using purified ACSS3 protein or cell lysates.
Common techniques for purifying ACSS3 protein include affinity chromatography, size exclusion chromatography, and ion exchange chromatography.
Customer Reviews (5)
Write a reviewUnbeatable price for the exceptional quality of the protein. Service was impeccable.
Outstanding quality at an affordable price. Impressed with the value for money.
Versatile and compatible. Fits various experimental setups."
"The performance of this protein is truly remarkable. Its consistent and reliable results have significantly contributed to the success of our research endeavors.
It eliminates background noise and provides clear and interpretable data.
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