Recombinant Human ADAM11 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: ADAM11-5276H
• Product Overview: ADAM11 MS Standard C13 and N15-labeled recombinant protein (NP_002381) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The encoded preproprotein is proteolytically processed to generate the mature protease. This gene represents a candidate tumor suppressor gene for human breast cancer based on its location within a minimal region of chromosome 17q21 previously defined by tumor deletion mapping. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 83.2 kDa
• AA Sequence: MRLLRRWAFAALLLSLLPTPGLGTQ GPAGALRWGGLPQLGGPGAPEVTEP SRLVRESSGGEVRKQQLDTRVRQEP PGGPPVHLAQVSFVIPAFNSNFTLD LELNHHLLSSQYVERHFSREGTTQH STGAGDHCYYQGKLRGNPHSFAALS TCQGLHGVFSDGNLTYIVEPQEVAG PWGAPQGPLPHLIYRTPLLPDPLGC REPGCLFAVPAQSAPPNRPRLRRKR QVRRGHPTVHSETKYVELIVINDHQ LFEQMRQSVVLTSNFAKSVVNLADV IYKEQLNTRIVLVAMETWADGDKIQ VQDDLLETLARLMVYRREGLPEPSD ATHLFSGRTFQSTSSGAAYVGGICS LSHGGGVNEYGNMGAMAVTLAQTLG QNLGMMWNKHRSSAGDCKCPDIWLG CIMEDTGFYLPRKFSRCSIDEYNQF LQEGGGSCLFNKPLKLLDPPECGNG FVEAGEECDCGSVQECSRAGGNCCK KCTLTHDAMCSDGLCCRRCKYEPRG VSCREAVNECDIAETCTGDSSQCPP NLHKLDGYYCDHEQGRCYGGRCKTR DRQCQVLWGHAAADRFCYEKLNVEG TERGSCGRKGSGWVQCSKQDVLCGF LLCVNISGAPRLGDLVGDISSVTFY HQGKELDCRGGHVQLADGSDLSYVE DGTACGPNMLCLDHRCLPASAFNFS TCPGSGERRICSHHGVCSNEGKCIC QPDWTGKDCSIHNPLPTSPPTGETE RYKGPSGTNIIIGSIAGAVLVAAIV LGGTGWGFKNIRRGRSGGATRTRPL EQKLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: ADAM11 ADAM metallopeptidase domain 11 [ Homo sapiens (human) ]
• Official Symbol: ADAM11
• Synonyms: ADAM11; ADAM metallopeptidase domain 11; a disintegrin and metalloproteinase domain 11, MDC; disintegrin and metalloproteinase domain-containing protein 11; metalloproteinase like; disintegrin like; cysteine rich protein; ADAM 11; MDC
• Gene ID: 4185
• mRNA Refseq: NM_002390
• Protein Refseq: NP_002381
• MIM: 155120
• UniProt ID: O75078

Reviews

04/10/2022

The ADAM11 proteins purchased from your company is suitable for ELISA.

02/25/2021

The staff had a good attitude, actively communicated with me and solved many technical problems.

Q&As

Where ADAM11 is highly expressed?

ADAM11 is widely expressed in hippocampus and cerebellum。

Where ADAM11 protein is abundantly expressed in humans?

ADAM11 is abundantly expressed in the cerebellar cortex and spinal cord, and is also expressed in small amounts in the retina and liver.

Which membrane is recommended for WB of ADAM11 protein?

You can choose PVDF membranes for western blotting.