Recombinant Human ADAMTS12 protein, His-tagged
Cat.No. : | ADAMTS12-1485H |
Product Overview : | Recombinant Human ADAMTS12 aa. (Gln823~Pro997 (Accession # P58397)) fused with N-terminal His tag was produced in E. coli cells. |
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Description : | This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS-1) motif. Individual members of this family differ in the number of C-terminal TS-1 motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains eight TS-1 motifs. It may play roles in pulmonary cells during fetal development or in tumor processes through its proteolytic activity or as a molecule potentially involved in regulation of cell adhesion. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Freeze-dried powder |
Molecular Mass : | Predicted Molecular Mass: 21.1kDa |
Protein length : | Gln823~Pro997 (Accession # P58397) |
Endotoxin : | <1.0EU per 1ug (determined by the LAL method) |
Purity : | >95% |
Applications : | SDS-PAGE; WB; ELISA; IP. |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
Storage buffer : | Supplied as lyophilized form in PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl. |
Reconstitution : | Reconstitute in sterile PBS, pH7.2-pH7.4. |
Isoelectric Point : | 8.5 |
Gene Name : | ADAMTS12 ADAM metallopeptidase with thrombospondin type 1 motif 12 [ Homo sapiens (human) ] |
Official Symbol : | ADAMTS12 |
Synonyms : | ADAMTS12; ADAM metallopeptidase with thrombospondin type 1 motif 12; PRO4389; A disintegrin and metalloproteinase with thrombospondin motifs 12; ADAM-TS 12; ADAM-TS12; ADAMTS-12; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 12 |
Gene ID : | 81792 |
mRNA Refseq : | NM_001324511.1 |
Protein Refseq : | NP_001311440.1 |
UniProt ID : | P58397 |
Products Types
◆ Recombinant Protein | ||
ADAMTS12-3006M | Recombinant Mouse ADAMTS12, His-tagged | +Inquiry |
ADAMTS12-298H | Recombinant Human ADAMTS12 Protein, GST-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (8)
Ask a questionWe will ship as soon as possible after your purchase.
ADAMTS12 blocked the mitogen activated protein kinase signaling pathway and prevented the tumorigenic effect of hepatocyte growth factor.
ADAMTS12 is more frequently studied in pancreatic and liver cancers.
We can customize the production products according to your needs.
Not expressed, ADAMTS12 protein is only widely expressed in malignant digestive system tumor tissues.
Yes, reducing the expression of ADAMTS12 interferes with the EMT process.
ADAMTS12 has the capabilities of tissue remodeling and cell migration and may work during normal inflammatory response.
You can contact our experts directly, and they will recommend suitable products for you according to your research purpose.
Customer Reviews (4)
Write a reviewI got this product at a discounted price, with some discounted prices. It also works well for ELISA.
Fast shipping, quality product, right price, worth buying!
Customer service patiently communicated with me and helped me to determine the experimental matters.
The purchased ADAMTS12 protein is suitable for WB experiments and I am satisfied with the results.
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