Recombinant Human ADAMTS2 Protein, His&Myc-tagged
Cat.No. : | ADAMTS2-1779H |
Product Overview : | Recombinant Human ADAMTS2 protein(NP_055059)(254-492aa), fused to N-terminal His tag and C-terminal Myc tag, was expressed in E. coli. |
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Source : | E. coli |
Species : | Human |
Tag : | His&Myc |
Form : | If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0. |
Molecular Mass : | 32.2 kDa |
Protein length : | 254-492aa |
AA Sequence : | RRRARRHAADDDYNIEVLLGVDDSV VQFHGKEHVQKYLLTLMNIVNEIYH DESLGAHINVVLVRIILLSYGKSMS LIEIGNPSQSLENVCRWAYLQQKPD TGHDEYHDHAIFLTRQDFGPSGMQG YAPVTGMCHPVRSCTLNHEDGFSSA FVVAHETGHVLGMEHDGQGNRCGDE VRLGSIMAPLVQAAFHRFHWSRCSQ QELSRYLHSYDCLLDDPFAHDWPAL PQLPGLHYSMNEQC |
Purity : | Greater than 90% as determined by SDS-PAGE. |
Storage : | Store at -20°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles. |
Reconstitution : | Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%. Customers could use it as reference. |
Gene Name : | ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2 [ Homo sapiens ] |
Official Symbol : | ADAMTS2 |
Synonyms : | ADAMTS2; ADAM metallopeptidase with thrombospondin type 1 motif, 2; a disintegrin like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 2; A disintegrin and metalloproteinase with thrombospondin motifs 2; ADAM TS2; ADAMTS 3; hPCPNI; NPI; PCINP; procollagen I N proteinase; procollagen N endopeptidase; procollagen I N-proteinase; procollagen N-endopeptidase; procollagen I/II amino propeptide-processing enzyme; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 2; PNPI; PCPNI; PCI-NP; PC I-NP; ADAM-TS2; ADAMTS-2; ADAMTS-3; DKFZp686F12218; |
Gene ID : | 9509 |
mRNA Refseq : | NM_014244 |
Protein Refseq : | NP_055059 |
MIM : | 604539 |
UniProt ID : | O95450 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionADAMTS2 has high sequence homology with ADAMTS14 and ADAMTS3.
Overexpression of ADAMTS2 significantly improves cardiac function and inhibits the development of myocardial hypertrophy, meaning that ADAMTS2 plays a protective role in the development of cardiac hypertrophy.
Yes, we are able to provide custom manufactured ADAMTS2 according to your needs.
ADAMTS2 affects the pathogenesis of cardiovascular disease and regulates myocardial hypertrophy.
We can custom produce ADAMTS2 (GST-tagged) for you.
ADAMTS2 is mainly expressed in connective tissues extending from the lymphatic network.
Mutations in the ADAMTS2 gene cause abnormal skin development in animals and congenital connective tissue dysplasia syndrome in humans.
Both cytokines TNF-α and TGF-β promote the secretion of ADAMTS2.
ADAMTS2 is widely used in cardiovascular disease research.
Due to the small molecular weight of the His tag, it generally does not affect the downstream application of the protein.
Customer Reviews (5)
Write a reviewThe protein received was tailored to my needs, allowing me to move forward with my research.
Technicians are able to provide helpful advice on product use.
High protein concentrations were received and the desired experimental results were obtained.
Smooth communication and timely shipment, allowing my experiment to be implemented as soon as possible.
The sales staff gave me good advice and allowed me to purchase products that met my research needs.
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