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Recombinant Human ADAMTS3, His-tagged

Cat.No. : ADAMTS3-3015H
Product Overview : A disintegrin and metalloproteinase with thrombospondin motifs 3 (ADAMTS3)
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Description : This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene is the major procollagen II N-propeptidase. A deficiency of this protein may be responsible for dermatosparaxis, a genetic defect of connective tissues. [provided by RefSeq, Jul 2008]
Source : E. Coli or Yeast
Species : Human
Tag : His
Form : This item requires custom production and lead time is between 5-9 weeks. We can custom produce according to your specifications.
Protein length : 1205
Purity : >90%
Notes : Small volumes of ADAMTS3 recombinant protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice.
Storage : Store at -20 degree C. For extended storage, store at -20 or -80 degree C.
Storage Buffer : PBS pH 7.4, 50% glycerol
Warning : This product is for research use only. Not for use in diagnostic or therapeutic procedures.
Gene Name : ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3 [ Homo sapiens ]
Official Symbol : ADAMTS3
Synonyms : ADAMTS3; ADAM metallopeptidase with thrombospondin type 1 motif, 3; a disintegrin like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 3; A disintegrin and metalloproteinase with thrombospondin motifs 3; ADAMTS 4; KIAA0366; ADAM-TS3; ADAMTS-3; PC II-NP; ADAM-TS 3; zinc metalloendopeptidase; procollagen II N-proteinase; procollagen II amino propeptide-processing enzyme; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 3; ADAMTS-4;
Gene ID : 9508
mRNA Refseq : NM_014243
Protein Refseq : NP_055058
MIM : 605011
UniProt ID : O15072
Chromosome Location : 4q21
Function : heparin binding; metal ion binding; metalloendopeptidase activity; peptidase activity; zinc ion binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (4)

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Which proteins have the highest homology to ADAMTS3? 02/23/2021

ADAMTS2, ADAMTS3 and ADAMTS14 had high homology.

What are the effects of a lack of ADAMTS3? 10/16/2020

ADAMTS3 is required for lymphangiogenesis and its defective function leads to abnormal lymphatic vessel development.

Where is ADAMTS3 mainly expressed? 09/09/2020

ADAMTS3 is widely expressed in connective tissues such as bone and tendon.

What is the function of ADAMTS3? 09/17/2019

ADAMTS3 is a procollagen N-propeptidase that is essential for the maturation of triple-helical collagen fibrils.

Customer Reviews (3)

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Reviews
12/25/2021

    Friendly customer service and detailed answers to all the questions I asked!

    05/15/2020

      Your company offers a one-stop shop and the process from purchase to receipt of the protein was very smooth!

      07/20/2019

        The purchased ADAMTS3 protein is suitable for WB experiments and I am satisfied with the results.

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