Recombinant Human ADAMTS3 Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | ADAMTS3-1965H |
Product Overview : | ADAMTS3 MS Standard C13 and N15-labeled recombinant protein (NP_055058) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
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Description : | This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature protease. This protease, a member of the procollagen aminopropeptidase subfamily of proteins, may play a role in the processing of type II fibrillar collagen in articular cartilage. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 135.6 kDa |
AA Sequence : | MVLLSLWLIAAALVEVRTSADGQAG NEEMVQIDLPIKRYREYELVTPVST NLEGRYLSHTLSASHKKRSARDVSS NPEQLFFNITAFGKDFHLRLKPNTQ LVAPGAVVEWHETSLVPGNITDPIN NHQPGSATYRIRKTEPLQTNCAYVG DIVDIPGTSVAISNCDGLAGMIKSD NEEYFIEPLERGKQMEEEKGRIHVV YKRSAVEQAPIDMSKDFHYRESDLE GLDDLGTVYGNIHQQLNETMRRRRH AGENDYNIEVLLGVDDSVVRFHGKE HVQNYLLTLMNIVNEIYHDESLGVH INVVLVRMIMLGYAKSISLIERGNP SRSLENVCRWASQQQRSDLNHSEHH DHAIFLTRQDFGPAGMQGYAPVTGM CHPVRSCTLNHEDGFSSAFVVAHET GHVLGMEHDGQGNRCGDETAMGSVM APLVQAAFHRYHWSRCSGQELKRYI HSYDCLLDDPFDHDWPKLPELPGIN YSMDEQCRFDFGVGYKMCTAFRTFD PCKQLWCSHPDNPYFCKTKKGPPLD GTECAAGKWCYKGHCMWKNANQQKQ DGNWGSWTKFGSCSRTCGTGVRFRT RQCNNPMPINGGQDCPGVNFEYQLC NTEECQKHFEDFRAQQCQQRNSHFE YQNTKHHWLPYEHPDPKKRCHLYCQ SKETGDVAYMKQLVHDGTHCSYKDP YSICVRGECVKVGCDKEIGSNKVED KCGVCGGDNSHCRTVKGTFTRTPRK LGYLKMFDIPPGARHVLIQEDEASP HILAIKNQATGHYILNGKGEEAKSR TFIDLGVEWDYNIEDDIESLHTDGP LHDPVIVLIIPQENDTRSSLTYKYI IHEDSVPTINSNNVIQEELDTFEWA LKSWSQCSKPCGGGFQYTKYGCRRK SDNKMVHRSFCEANKKPKPIRRMCN IQECTHPLWVAEEWEHCTKTCGSSG YQLRTVRCLQPLLDGTNRSVHSKYC MGDRPESRRPCNRVPCPAQWKTGPW SECSVTCGEGTEVRQVLCRAGDHCD GEKPESVRACQLPPCNDEPCLGDKS IFCQMEVLARYCSIPGYNKLCCESC SKRSSTLPPPYLLEAAETHDDVISN PSDLPRSLVMPTSLVPYHSETPAKK MSLSSISSVGGPNAYAAFRPNSKPD GANLRQRSAQQAGSKTVRLVTVPSS PPTKRVHLSSASQMAAASFFAASDS IGASSQARTSKKDGKIIDNRRPTRS STLERTRTRPLEQKLISEEDLAAND ILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif 3 [ Homo sapiens (human) ] |
Official Symbol : | ADAMTS3 |
Synonyms : | ADAMTS3; ADAM metallopeptidase with thrombospondin type 1 motif, 3; a disintegrin like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 3; A disintegrin and metalloproteinase with thrombospondin motifs 3; ADAMTS 4; KIAA0366; ADAM-TS3; ADAMTS-3; PC II-NP; ADAM-TS 3; zinc metalloendopeptidase; procollagen II N-proteinase; procollagen II amino propeptide-processing enzyme; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 3; ADAMTS-4; |
Gene ID : | 9508 |
mRNA Refseq : | NM_014243 |
Protein Refseq : | NP_055058 |
MIM : | 605011 |
UniProt ID : | O15072 |
Products Types
◆ Recombinant Protein | ||
Adamts3-1529M | Recombinant Mouse Adamts3 Protein, Myc/DDK-tagged | +Inquiry |
ADAMTS3-280H | Recombinant Human ADAMTS3 Protein, His (Fc)-Avi-tagged | +Inquiry |
ADAMTS3-01H | Recombinant Human ADAMTS3 Protein, Myc/DDK-tagged | +Inquiry |
ADAMTS3-02H | Recombinant Human ADAMTS3 Protein, Flag-tagged | +Inquiry |
ADAMTS3-736H | Recombinant Human ADAMTS3 | +Inquiry |
◆ Lysates | ||
ADAMTS3-9030HCL | Recombinant Human ADAMTS3 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (4)
Ask a questionADAMTS2, ADAMTS3 and ADAMTS14 had high homology.
ADAMTS3 is required for lymphangiogenesis and its defective function leads to abnormal lymphatic vessel development.
ADAMTS3 is widely expressed in connective tissues such as bone and tendon.
ADAMTS3 is a procollagen N-propeptidase that is essential for the maturation of triple-helical collagen fibrils.
Customer Reviews (3)
Write a reviewFriendly customer service and detailed answers to all the questions I asked!
Your company offers a one-stop shop and the process from purchase to receipt of the protein was very smooth!
The purchased ADAMTS3 protein is suitable for WB experiments and I am satisfied with the results.
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