Recombinant Human ADAMTS8, His-tagged
Cat.No. : | ADAMTS8-3009H |
Product Overview : | A Disintegrin And Metalloproteinase With Thrombospondin 8 (ADAMTS8) |
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Description : | This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains two C-terminal TS motifs, and disrupts angiogenesis in vivo. A number of disorders have been mapped in the vicinity of this gene, most notably lung neoplasms. [provided by RefSeq, Jul 2008] |
Source : | E. Coli |
Species : | Human |
Tag : | His |
Form : | Supplied as lyophilized form in PBS,pH7.4, containing 5% sucrose, 0.01% sarcosyl. |
Molecular Mass : | 7.7kDa |
Protein length : | 889 |
Endotoxin : | <1.0eu per 1ug (determined by the lal</1.0eu |
Purity : | >95% |
Applications : | SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP) |
Notes : | Small volumes of ADAMTS8 recombinant protein may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition. |
Reconstitution : | Reconstitute in sterile PBS, pH7.2-pH7.4. |
Warning : | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Gene Name : | ADAMTS8 ADAM metallopeptidase with thrombospondin type 1 motif, 8 [ Homo sapiens ] |
Official Symbol : | ADAMTS8 |
Synonyms : | ADAMTS8; ADAM metallopeptidase with thrombospondin type 1 motif, 8; a disintegrin like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 8; A disintegrin and metalloproteinase with thrombospondin motifs 8; ADAM TS8; FLJ41712; METH2; METH-2; METH-8; ADAMTS-8; ADAM-TS 8; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 8; ADAM-TS8; |
Gene ID : | 11095 |
mRNA Refseq : | NM_007037 |
Protein Refseq : | NP_008968 |
MIM : | 605175 |
UniProt ID : | Q9UP79 |
Chromosome Location : | 11q25 |
Function : | heparin binding; integrin binding; low affinity phosphate transmembrane transporter activity; metal ion binding; metalloendopeptidase activity; metallopeptidase activity; peptidase activity; zinc ion binding; |
Products Types
◆ Recombinant Protein | ||
Adamts8-1531M | Recombinant Mouse Adamts8 Protein, Myc/DDK-tagged | +Inquiry |
ADAMTS8-29H | Recombinant Human ADAMTS8 Protein, MYC/DDK-tagged | +Inquiry |
ADAMTS8-281H | Recombinant Human ADAMTS8 Protein, His (Fc)-Avi-tagged | +Inquiry |
Adamts8-3016M | Recombinant Mouse Adamts8, His-tagged | +Inquiry |
ADAMTS8-0160H | Recombinant Human ADAMTS8 Protein (Leu832-Leu889), N-His-tagged | +Inquiry |
◆ Lysates | ||
ADAMTS8-9027HCL | Recombinant Human ADAMTS8 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionADAMTS8 shows anti-angiogenesis and inhibition of endothelial cell production
ADAMTS8 is used in more studies of heart and cardiovascular diseases
ADAMTS8 used to be called METH-2.
ADAMTS8 is predominantly expressed in the lungs and heart
Pre-structural domains, metalloproteinase structural domains, disintegrin-like structural domains, central thrombospondin-like motifs, cysteine-rich structural domains, spacer region structural domains and C-terminal motifs
Customer Reviews (3)
Write a reviewThe technician modified my experimental protocol so that my experiment went smoothly.
Very good after-sales service to get my experiments going!
The protein composition was stable and concentrated, allowing me to obtain satisfactory experimental results.
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