Recombinant Human ALX4 Protein Pre-coupled Magnetic Beads
Cat.No. : | ALX4-2459H-B |
Product Overview : | The Recombnant protein was conjugated to magnetic beads. This ready-to-use, pre-coupled magnetic beads are in uniform particle size and narrow size distribution with large surface area, which is conducive to convenient and fast capture target molecules with high specificity and achieve magnetic separation. This product can be equipped with automation equipment for high-throughput operations. |
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Source : | HEK293 |
Species : | Human |
Form : | Solution |
Particle size : | ~2 μm |
Beads Surface : | Hydrophilic |
Capacity : | > 200 pmol rabbit IgG/ mg beads |
Applications : | Immunoassay, In vitro diagnostics, cell sorting, Immunoprecipitation/Co-precipitation, Protein/antibody separation and purification. |
Stability : | Stable for at least 6 months from the date of receipt of the product under proper storage and handling conditions. |
Storage : | 2-8℃. Do not to freeze thaw the Beads |
Concentration : | 10mg beads/mL |
Storage Buffer : | PBS buffer |
Gene Name : | ALX4 ALX homeobox 4 [ Homo sapiens ] |
Official Symbol : | ALX4 |
Gene ID : | 60529 |
mRNA Refseq : | NM_021926.3 |
Protein Refseq : | NP_068745.2 |
MIM : | 605420 |
UniProt ID : | Q9H161 |
Products Types
◆ Recombinant Protein | ||
ALX4-2459H | Recombinant Human ALX4 Protein, His (Fc)-Avi-tagged | +Inquiry |
ALX4-511H | Recombinant Human ALX4 protein, GST-tagged | +Inquiry |
ALX4-5737C | Recombinant Chicken ALX4 | +Inquiry |
ALX4-754H | Recombinant Human ALX4 | +Inquiry |
◆ Lysates | ||
ALX4-8889HCL | Recombinant Human ALX4 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionALX4 interacts with various co-regulatory proteins and transcription factors, forming complexes that modulate gene expression and cellular processes critical for embryonic development.
ALX4 recognizes specific DNA binding motifs, such as homeobox motifs, and binds to regulatory regions of target genes to regulate their transcriptional activity.
Gain-of-function or loss-of-function mutations in ALX4 can disrupt normal embryonic development, leading to craniofacial abnormalities, limb defects, or skeletal malformations.
ALX4 binding sites are associated with specific epigenetic modifications, such as DNA methylation or histone modifications, which contribute to the regulation of ALX4-mediated transcriptional activity.
ALX4 integrates with signaling pathways, such as BMP, Wnt, or FGF signaling, to modulate gene expression and influence cellular behaviors during embryogenesis.
Pharmacological or genetic modulation of ALX4 activity may have therapeutic implications for craniofacial disorders, skeletal dysplasias, or regenerative medicine, but further studies are needed to explore these possibilities.
ALX4 forms transcriptional complexes with other transcription factors and co-regulators, such as MSX1 or RUNX2, to coordinate gene expression programs essential for craniofacial development, skeletal patterning, and limb morphogenesis.
ALX4 exhibits a dynamic spatiotemporal expression pattern during embryonic development, with prominent expression in craniofacial structures, limb buds, and axial skeleton.
ALX4 regulates cell proliferation, differentiation, and migration during embryogenesis through various molecular mechanisms, including interactions with cell cycle regulators, morphogen gradients, or cytoskeletal components.
ALX4 regulates the expression of genes involved in craniofacial development, skeletal patterning, and limb formation, including those encoding transcription factors, extracellular matrix components, or signaling molecules.
Customer Reviews (3)
Write a reviewCompatibility with small sample volumes for limited samples.
High specificity in protein target identification.
Stable and reliable reagents for reproducible results.
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