Recombinant Human ANKS1A, GST-tagged
Cat.No. : | ANKS1A-9677H |
Product Overview : | Recombinant Human ANKS1A protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | 221-570a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A [ Homo sapiens ] |
Official Symbol : | ANKS1A |
Synonyms : | ANKS1A; ankyrin repeat and sterile alpha motif domain containing 1A; ANKS1, ankyrin repeat and SAM domain containing 1 , ankyrin repeat and sterile alpha motif domain containing 1; ankyrin repeat and SAM domain-containing protein 1A; KIAA0229; Odin; ankyrin repeat and SAM domain containing 1; ANKS1; MGC42354; |
Gene ID : | 23294 |
mRNA Refseq : | NM_015245 |
Protein Refseq : | NP_056060 |
MIM : | 608994 |
UniProt ID : | Q92625 |
Chromosome Location : | 6p21.31 |
Function : | ephrin receptor binding; |
Products Types
◆ Recombinant Protein | ||
ANKS1A-611H | Recombinant Human ANKS1A protein, GST-tagged | +Inquiry |
ANKS1-610H | Recombinant Human ANKS1 protein, GST-tagged | +Inquiry |
◆ Lysates | ||
ANKS1A-83HCL | Recombinant Human ANKS1A cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionMutations in the ANKS1A gene have been associated with neurodevelopmental disorders, including autism spectrum disorders and intellectual disabilities. These findings suggest a potential involvement of Anks1A in the pathogenesis of these conditions. However, further research is needed to understand the precise mechanisms underlying these associations.
Yes, Anks1A is implicated in various cellular processes beyond cytoskeletal organization. It is believed to have roles in intracellular signaling, protein-protein interactions, calcium signaling, and potentially synaptic development and function.
Current research on Anks1A protein focuses on understanding its role in cellular processes, its interactions with other proteins, and its potential involvement in neurodevelopmental disorders. Studies are being conducted to investigate the mechanisms of Anks1A function, its regulation, and its contribution to disease pathology.
Yes, Anks1A has a paralog called Anks1B (Ankyrin repeat and SAM domain-containing protein 1B) that shares high sequence similarity and similar domain architecture. Anks1B is also involved in cytoskeletal organization and protein-protein interactions, but its specific functions may differ from Anks1A.
Yes, mutations in the ANKS1A gene have been identified in individuals with neurodevelopmental disorders such as autism spectrum disorders and intellectual disabilities. These mutations can disrupt the normal function of Anks1A and suggest a potential link between ANKS1A variants and disease phenotypes.
Anks1A is primarily localized in the cytoplasm of the cell.
Anks1A protein contains several structural domains including multiple ankyrin repeats that are involved in protein-protein interactions, and a SAM domain (sterile alpha motif) that is implicated in protein-protein interactions and may have a role in intracellular signal transduction.
Yes, animal models such as knockout mice lacking the Anks1A gene have been generated to study its function. These models help researchers investigate the physiological effects of Anks1A loss and better understand its role in development and disease.
Anks1A contains several functional domains, including ankyrin repeats and SAM (sterile alpha motif) domains. Ankyrin repeats are responsible for protein-protein interactions, and SAM domains are involved in various cellular processes, including protein interactions and signal transduction.
Yes, several proteins have been reported to interact with Anks1A. Some of these interactors include TRPV4, p105, and Kank1/ANKS1B. These interactions suggest that Anks1A may play a role in calcium signaling, NF-κB pathway signaling, and cytoskeletal organization.
Customer Reviews (4)
Write a reviewThis protein has become an invaluable asset in my research, offering great versatility in its applications.
the ANKS1A protein stands out for its excellent quality, exceptional technical support, and wide range of applications.
It has become an indispensable tool in my experiments, consistently meeting my needs and providing valuable insights.
Its robust performance has significantly accelerated my research progress and contributed to the advancement of my scientific understanding.
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