Recombinant Human AOC2 Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | AOC2-4669H |
Product Overview : | AOC2 MS Standard C13 and N15-labeled recombinant protein (NP_033720) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
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Description : | Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes and ammonia in the presence of copper and quinone cofactor. This gene shows high sequence similarity to copper amine oxidases from various species ranging from bacteria to mammals. The protein contains several conserved motifs including the active site of amine oxidases and the histidine residues that likely bind copper. It may be a critical modulator of signal transmission in retina, possibly by degrading the biogenic amines dopamine, histamine, and putrescine. This gene may be a candidate gene for hereditary ocular diseases. Alternate splicing results in multiple transcript variants. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 83.5 kDa |
AA Sequence : | MHLKIVLAFLALSLITIFALAYVLL TSPGGSSQPPHCPSVSHRAQPWPHP GQSQLFADLSREELTAVMRFLTQRL GPGLVDAAQAQPSDNCIFSVELQLP PKAAALAHLDRGSPPPAREALAIVL FGGQPQPNVSELVVGPLPHPSYMRD VTVERHGGPLPYHRRPVLRAEFTQM WRHLKEVELPKAPIFLSSTFNYNGS TLAAVHATPRGLRSGDRATWMALYH NISGVGLFLHPVGLELLLDHRALDP AHWTVQQVFYLGHYYADLGQLEREF KSGRLEVVRVPLPPPNGASSLRSRN SPGPLPPLQFSPQGSQYSVQGNLVV SSLWSFTFGHGVFSGLRIFDVRFQG ERIAYEVSVQECVSIYGADSPKTML TRYLDSSFGLGRNSRGLVRGVDCPY QATMVDIHILVGKGAVQLLPGAVCV FEEAQGLPLRRHHNYLQNHFYGGLA SSALVVRSVSSVGNYDYIWDFVLYP NGALEGRVHATGYINTAFLKGGEEG LLFGNRVGERVLGTVHTHAFHFKLD LDVAGLKNWVVAEDVVFKPVAAPWN PEHWLQRPQLTRQVLGKEDLTAFSL GSPLPRYLYLASNQTNAWGHQRGYR IQIHSPLGIHIPLESDMERALSWGR YQLVVTQRKEEESQSSSIYHQNDIW TPTVTFADFINNETLLGEDLVAWVT ASFLHIPHAEDIPNTVTLGNRVGFL LRPYNFFDEDPSIFSPGSVYFEKGQ DAGLCSINPVACLPDLAACVPDLPP FSYHGFTRTRPLEQKLISEEDLAAN DILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | AOC2 amine oxidase copper containing 2 [ Homo sapiens (human) ] |
Official Symbol : | AOC2 |
Synonyms : | AOC2; amine oxidase, copper containing 2 (retina-specific); retina-specific copper amine oxidase; DAO2; RAO; SSAO; semicarbazide-sensitive amine oxidase; |
Gene ID : | 314 |
mRNA Refseq : | NM_009590 |
Protein Refseq : | NP_033720 |
MIM : | 602268 |
UniProt ID : | O75106 |
Products Types
◆ Recombinant Protein | ||
Aoc2-1652M | Recombinant Mouse Aoc2 Protein, Myc/DDK-tagged | +Inquiry |
AOC2-349H | Recombinant Human AOC2 Protein, His (Fc)-Avi-tagged | +Inquiry |
AOC2-590M | Recombinant Mouse AOC2 Protein, His (Fc)-Avi-tagged | +Inquiry |
AOC2-176H | Recombinant Human AOC2 Protein, His-tagged | +Inquiry |
AOC2-1723M | Recombinant Mouse AOC2 Protein | +Inquiry |
◆ Lysates | ||
AOC2-8823HCL | Recombinant Human AOC2 293 Cell Lysate | +Inquiry |
AOC2-8822HCL | Recombinant Human AOC2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (18)
Ask a questionAOC2 has important application potential in many fields such as biological science and medical field, and has a very wide application prospect.
AOC2 has potential therapeutic effects in the treatment of kidney disease and cancer.
At present, the specific application of AOC2 in tumor therapy still needs to be further studied.
At present, the clinical study of AOC2 in the treatment of tumor has not been conclusive, and further research is needed.
The dose of AOC2 needs to be adjusted individually according to the clinical situation. In general, use strictly according to the doctor's advice.
Yes, some mature production technologies have been developed and the corresponding processes have been applied on a large scale.
AOC2 is a recombinant human protein from exons, and its structure and function conform to physiological characteristics.
AOC2 has been implicated in the occurrence and development of certain kidney diseases, as well as in the occurrence and development of tumors.
AOC2 has higher biological activity and stability compared with other similar biological products.
Yes, AOC2 can be mass-produced through cell culture, genetic engineering and other technologies.
It is necessary to go through the relevant approval process to obtain the approval of the national regulatory authority for use.
It is necessary to solve relevant technical problems by strengthening research and developing new process technologies.
AOC2 is used in many fields such as kidney disease treatment and tumor treatment.
AOC2 can alleviate physiological processes such as renal fibrosis and inflammatory response, and has a potential role in the prevention and treatment of kidney diseases.
No studies have shown that AOC2 has adverse effects on human reproductive health.
The regulation of AOC2 on intracellular oxygen molecules is related to anti-oxidative stress, and can also affect cell cycle, proliferation and apoptosis.
Yes, AOC2 needs to undergo relevant clinical trials to evaluate its efficacy and safety.
Recombinant AOC2 proteins may have some side effects, such as headache, nausea, pain, etc., but they are relatively rare.
Customer Reviews (3)
Write a reviewImmunogenicity of AOC2 is very weak, does not cause an immune response, and is very safe.
The catalytic activity of AOC2 is very excellent, and it can be widely used in various chemical reactions, and has high practical value.
Repeatability is very good, can reduce unnecessary repeated experiments, improve the efficiency of the experiment.
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