Recombinant Human ARMCX2 293 Cell Lysate

• Cat.No.: ARMCX2-8695HCL

Specification

• Description: Antigen standard for armadillo repeat containing, X-linked 2 (ARMCX2) is a lysate prepared from HEK293T cells transiently transfected with a TrueORF gene-carrying pCMV plasmid and then lysed in RIPA Buffer. Protein concentration was determined using a colorimetric assay. The antigen control carries a C-terminal Myc/DDK tag for detection.
• Source: HEK 293 cells
• Species: Human
• Components: This product includes 3 vials: 1 vial of gene-specific cell lysate, 1 vial of control vector cell lysate, and 1 vial of loading buffer. Each lysate vial contains 0.1 mg lysate in 0.1 ml (1 mg/ml) of RIPA Buffer (50 mM Tris-HCl pH7.5, 250 mM NaCl, 5 mM EDTA, 50 mM NaF, 1% NP40). The loading buffer vial contains 0.5 ml 2X SDS Loading Buffer (125 mM Tris-Cl, pH6.8, 10% glycerol, 4% SDS, 0.002% Bromophenol blue, 5% beta-mercaptoethanol).
• Size: 0.1 mg
• Storage Instruction: Store at -80°C. Minimize freeze-thaw cycles. After addition of 2X SDS Loading Buffer, the lysates can be stored at -20°C. Product is guaranteed 6 months from the date of shipment.
• Applications: ELISA, WB, IP. WB: Mix equal volume of lysates with 2X SDS Loading Buffer. Boil the mixture for 10 min before loading (for membrane protein lysates, incubate the mixture at room temperature for 30 min). Load 5 ug lysate per lane.

Gene Information

• Gene Name: ARMCX2 armadillo repeat containing, X-linked 2 [ Homo sapiens ]
• Official Symbol: ARMCX2
• Synonyms: armadillo repeat containing, X-linked 2; arm protein lost in epithelial cancers, X chromosome, 2; ALEX2; armadillo repeat protein ALEX2; KIAA0512; armadillo repeat-containing X-linked protein 2; ARM protein lost in epithelial cancers on chromosome X 2; Protein ALEX2
• Gene ID: 9823
• mRNA Refseq: NM_014782.5
• Protein Refseq: NP_055597.1
• MIM: 300363
• UniProt ID: Q7L311
• Chromosome Location: Xq21.33-q22.2

Reviews

11/14/2022

Their knowledgeable and responsive team stands ready to address any concerns or challenges I may encounter.

07/01/2020

To further elevate my confidence, the manufacturer's commitment to offering exemplary technical support is truly commendable.

04/03/2018

Its purity, stability, and functional integrity are of the highest standard, instilling confidence in generating accurate and insightful results crucial for my research objectives.

05/06/2017

The use of ARMCX2 protein in such analyses provides valuable structural insights that contribute to the elucidation of ANO2's functional mechanisms and potential drug targeting sites.

02/09/2017

ARMCX2 protein has shown great utility in protein electron microscopy structure analysis.

05/26/2016

It enables accurate detection and quantification of ARMCX2 protein levels in samples, providing crucial insights into its expression, regulation, and potential functional changes under different experimental conditions.

Q&As

Can changes in ARMCX2 expression levels affect neuronal development or function?

The specific impact of changes in ARMCX2 expression levels on neuronal development or function is not yet clearly understood. Further research is necessary to explore the potential roles of ARMCX2 in these processes.

Are there any animal models available for studying the function of ARMCX2?

There are currently no specific animal models available for studying the function of ARMCX2. Generating animal models, such as knockout mice, could be useful for investigating its biological roles in vivo.

Where is the ARMCX2 protein predominantly expressed?

The ARMCX2 protein is mainly expressed in the brain, particularly in regions such as the cerebral cortex, hippocampus, and cerebellum. It has also been detected in other tissues to a lesser extent, including the heart, kidney, and testis.

Does the ARMCX2 protein have any known interacting partners?

Currently, there is limited information available regarding known interacting partners of the ARMCX2 protein. Identifying and characterizing its protein-protein interactions is an area of ongoing research.

Is the expression of the ARMCX2 gene tissue-specific?

Yes, the expression of the ARMCX2 gene is tissue-specific, with the highest expression levels observed in the brain. However, low levels of ARMCX2 expression have been reported in other tissues as well.