Recombinant Human ARMCX2 protein, GST-tagged

• Cat.No.: ARMCX2-834H
• Product Overview: Human ARMCX2 partial ORF ( NP_055597, 508 a.a. - 599 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a protein containing a potential N-terminal transmembrane domain and multiple armadillo (arm) repeats. Proteins containing arm repeats are involved in development, maintenance of tissue integrity, and tumorigenesis. This gene is located in a cluster of related genes on chromosome X. There is a pseudogene for this gene on chromosome 7. Alternative splicing in the 5' UTR results in multiple transcript variants encoding the same protein. [provided by RefSeq, Aug 2013]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 35.86 kDa
• AA Sequence: NSIANFFRLLSQGGGKIKVEILKIL SNFAENPDMLKKLLSTQVPASFSSL YNSYVESEILINALTLFEIIYDNLR AEVFNYREFNKGSLFYL
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: ARMCX2 armadillo repeat containing, X-linked 2 [ Homo sapiens ]
• Official Symbol: ARMCX2
• Synonyms: armadillo repeat containing, X-linked 2; arm protein lost in epithelial cancers, X chromosome, 2; ALEX2; armadillo repeat protein ALEX2; KIAA0512; armadillo repeat-containing X-linked protein 2; ARM protein lost in epithelial cancers on chromosome X 2; Protein ALEX2
• Gene ID: 9823
• mRNA Refseq: NM_014782.5
• Protein Refseq: NP_055597.1
• MIM: 300363
• UniProt ID: Q7L311

Reviews

11/14/2022

Their knowledgeable and responsive team stands ready to address any concerns or challenges I may encounter.

07/01/2020

To further elevate my confidence, the manufacturer's commitment to offering exemplary technical support is truly commendable.

04/03/2018

Its purity, stability, and functional integrity are of the highest standard, instilling confidence in generating accurate and insightful results crucial for my research objectives.

05/06/2017

The use of ARMCX2 protein in such analyses provides valuable structural insights that contribute to the elucidation of ANO2's functional mechanisms and potential drug targeting sites.

02/09/2017

ARMCX2 protein has shown great utility in protein electron microscopy structure analysis.

05/26/2016

It enables accurate detection and quantification of ARMCX2 protein levels in samples, providing crucial insights into its expression, regulation, and potential functional changes under different experimental conditions.

Q&As

Can changes in ARMCX2 expression levels affect neuronal development or function?

The specific impact of changes in ARMCX2 expression levels on neuronal development or function is not yet clearly understood. Further research is necessary to explore the potential roles of ARMCX2 in these processes.

Are there any animal models available for studying the function of ARMCX2?

There are currently no specific animal models available for studying the function of ARMCX2. Generating animal models, such as knockout mice, could be useful for investigating its biological roles in vivo.

Where is the ARMCX2 protein predominantly expressed?

The ARMCX2 protein is mainly expressed in the brain, particularly in regions such as the cerebral cortex, hippocampus, and cerebellum. It has also been detected in other tissues to a lesser extent, including the heart, kidney, and testis.

Does the ARMCX2 protein have any known interacting partners?

Currently, there is limited information available regarding known interacting partners of the ARMCX2 protein. Identifying and characterizing its protein-protein interactions is an area of ongoing research.

Is the expression of the ARMCX2 gene tissue-specific?

Yes, the expression of the ARMCX2 gene is tissue-specific, with the highest expression levels observed in the brain. However, low levels of ARMCX2 expression have been reported in other tissues as well.