Recombinant Human ASAP3 Protein Pre-coupled Magnetic Beads

• Cat.No.: ASAP3-385H-B
• Product Overview: The Recombnant protein was conjugated to magnetic beads. This ready-to-use, pre-coupled magnetic beads are in uniform particle size and narrow size distribution with large surface area, which is conducive to convenient and fast capture target molecules with high specificity and achieve magnetic separation. This product can be equipped with automation equipment for high-throughput operations.

Specification

• Source: HEK293
• Species: Human
• Form: Solution
• Particle size: ~2 μm
• Beads Surface: Hydrophilic
• Capacity: > 200 pmol rabbit IgG/ mg beads
• Applications: Immunoassay, In vitro diagnostics, cell sorting, Immunoprecipitation/Co-precipitation, Protein/antibody separation and purification.
• Stability: Stable for at least 6 months from the date of receipt of the product under proper storage and handling conditions.
• Storage: 2-8℃. Do not to freeze thaw the Beads
• Concentration: 10mg beads/mL
• Storage Buffer: PBS buffer

Gene Information

• Gene Name: ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3 [ Homo sapiens (human) ]
• Official Symbol: ASAP3
• Synonyms: ACAP4; UPLC1; CENTB6; DDEFL1
• Gene ID: 55616
• mRNA Refseq: NM_017707.4
• Protein Refseq: NP_060177.2
• MIM: 616594
• UniProt ID: Q8TDY4

Reviews

03/15/2022

The outstanding level of customer service adds extra reassurance and confidence in using the ASAP3 protein for my scientific investigations.

09/29/2019

With the ASAP3 protein and its accompanying technical assistance, I am confident that I can achieve successful outcomes for my research endeavors.

10/23/2018

The ASAP3 protein offers numerous advantages in trials and research studies, making it an excellent choice for scientists in need of reliable and high-quality experimental materials.

Q&As

Is ASAP3 expressed in immune cells?

ASAP3 has been found in immune cells, indicating its potential involvement in immune responses, though its exact functions in this context remain to be fully elucidated.

Does ASAP3 play a role in cell adhesion?

Yes, ASAP3 is involved in cell adhesion processes by regulating the internalization and recycling of adhesion molecules, such as integrins, at the plasma membrane.

Can ASAP3 be regulated by post-translational modifications?

Yes, ASAP3 can undergo phosphorylation, acetylation, and ubiquitination, which can affect its stability, activity, and protein-protein interactions.

How does ASAP3 regulate membrane trafficking?

ASAP3 stimulates the GTP hydrolysis of Arf6, leading to its inactivation and subsequent modulation of vesicle trafficking pathways, including endocytosis and recycling.

Is ASAP3 involved in cancer progression?

ASAP3 has been suggested to play a role in cancer cell invasion and metastasis due to its influence on cell migration, adhesion, and the actin cytoskeleton.

Are there any genetic variations associated with ASAP3?

Genetic variations in ASAP3 have been identified, and some studies have linked them to certain diseases or phenotypes, although further research is needed to establish definitive associations.

Can ASAP3 interact with other proteins?

Yes, ASAP3 can interact with various proteins involved in membrane trafficking, including clathrin, AP1, AP2, and several adaptor proteins.

Does ASAP3 play a role in neuronal processes?

ASAP3 expression has been observed in neurons, suggesting a potential role in neuronal development, synaptic plasticity, or other neuronal processes, although more investigation is required.