Recombinant Human ATP5C1 protein, GST-tagged
Cat.No. : | ATP5C1-978H |
Product Overview : | Human ATP5C1 full-length ORF ( AAH00931, 1 a.a. - 298 a.a.) recombinant protein with GST-tag at N-terminal. |
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Description : | This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel consists of three main subunits (a, b, c). This gene encodes the gamma subunit of the catalytic core. Alternatively spliced transcript variants encoding different isoforms have been identified. This gene also has a pseudogene on chromosome 14. [provided by RefSeq, Jul 2008] |
Source : | Wheat Germ |
Species : | Human |
Tag : | GST |
Molecular Mass : | 58.52 kDa |
AA Sequence : | MFSRAGVAGLSAWTLQPQWIQVRNM ATLKDITRRLKSIKNIQKITKSMKM VAAAKYARAERELKPARIYGLGSLA LYEKADIKGPEDKKKHLLIGVSSDR GLCGAIHSSIAKQMKSEVATLTAAG KEVMLVGIGDKIRGILYRTHSDQFL VAFKEVGRKPPTFGDASVIALELLN SGYEFDEGSIIFNKFRSVISYKTEE KPIFSLNTVASADSMSIYDDIDADV LQNYQEYNLANIIYYSLKESTTSEQ SARMTAMDNASKNASEMIDKLTLTF NRTRQAVITKELIEIISGAAALD |
Applications : | Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array |
Notes : | Best use within three months from the date of receipt of this protein. |
Storage : | Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
Storage Buffer : | 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
Gene Name : | ATP5C1 ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1 [ Homo sapiens ] |
Official Symbol : | ATP5C1 |
Synonyms : | ATP5C1; ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1; ATP5C, ATP5CL1; ATP synthase subunit gamma, mitochondrial; F-ATPase gamma subunit; ATP synthase gamma chain, mitochondrial; mitochondrial ATP synthase, gamma subunit 1; ATP5C; ATP5CL1; |
Gene ID : | 509 |
mRNA Refseq : | NM_001001973 |
Protein Refseq : | NP_001001973 |
MIM : | 108729 |
UniProt ID : | P36542 |
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◆ Lysates | ||
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionATP5C1 expression and function are affected by a variety of regulatory mechanisms, including regulation of transcription factors and epigenetic modifications.
Yes, ATP5C1 expression levels may be associated with the development and progression of certain diseases.
ATP5C1 is highly expressed in multiple tissues and organs, especially metabolically active tissues such as heart, liver, and brain.
Yes, ATP5C1 gene mutations are associated with certain neurological diseases such as Parkinson's disease, cerebral ischemia, etc.
It may play a role in tumor cell metabolism and energy supply.
ATP5C1 protein may be related to the occurrence and progression of metabolic diseases such as obesity and diabetes.
Customer Reviews (3)
Write a reviewThe exceptional stability of this protein makes it an invaluable tool for a wide range of applications.
Due to the wide application of proteins, researchers can conduct research in more fields and broaden the horizon of scientific research.
Because the extraordinary activity of proteins makes them valuable tools for a wide range of applications.
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