Recombinant Human CFL2 protein(Ala2-Leu166), His-tagged

• Cat.No.: CFL2-6905H
• Product Overview: Recombinant Human CFL2 (Q9Y281-1) (Ala 2-Leu 166) was expressed in E. coli, with a polyhistidine tag at the N-terminus.

Specification

• Source: E. coli
• Species: Human
• Tag: N-His
• Protein length: Ala2-Leu166
• Form: Lyophilized from sterile PBS, pH 7.5. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
• Molecular Mass: The recombinant human CFL2 consisting of 180 amino acids and has a calculated molecular mass of 20.4 kDa. The apparent molecular mass of the protein is approximately 21 kDa in SDS-PAGE under reducing conditions.
• Purity: > 98 % as determined by SDS-PAGE
• Storage: Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.

Gene Information

• Gene Name: CFL2 cofilin 2 (muscle) [ Homo sapiens ]
• Official Symbol: CFL2
• Synonyms: CFL2; cofilin 2 (muscle); cofilin-2; cofilin, muscle isoform; NEM7
• Gene ID: 1073
• mRNA Refseq: NM_001243645
• Protein Refseq: NP_001230574
• MIM: 601443
• UniProt ID: Q9Y281

Reviews

05/23/2022

It has been extensively used in protein-protein interaction studies, enzymatic assays, and structural analyses, showcasing its reliability and adaptability in diverse research areas.

11/13/2021

I am certain of obtaining reliable and reproducible results, enabling me to contribute to scientific progress and make new discoveries.

11/07/2017

I highly recommend the CFL2 Protein for its outstanding performance in ELISA assays.

Q&As

Are there any ongoing clinical trials targeting CFL2 for therapeutic purposes?

It's important to check current clinical trial databases for the latest information, but research exploring CFL2 as a therapeutic target is ongoing.

How does CFL2 relate to cardiac diseases?

CFL2 is involved in maintaining the structure and function of cardiac muscle cells, and its dysregulation has been linked to conditions such as cardiomyopathies.

Are there diagnostic applications for CFL2 in muscle-related disorders?

Research suggests that analyzing CFL2 levels and activity could serve as diagnostic markers for certain muscle-related disorders.

How does CFL2 interact with other proteins in the context of muscle function?

CFL2 interacts with actin and other regulatory proteins to modulate the dynamics of the actin cytoskeleton, influencing cellular processes crucial for muscle function.

Can CFL2 be a potential therapeutic target for muscle-related disorders?

Investigating CFL2 as a therapeutic target is an active area of research, with the aim of developing interventions for conditions characterized by impaired muscle function.