Recombinant Human CHAC1 Protein, GST-Tagged

• Cat.No.: CHAC1-1199H
• Product Overview: Human CHAC1 full-length ORF (NP_077016.1, 1 a.a. - 222 a.a.) recombinant protein with GST tag at N-terminal.

Specification

• Description: This gene encodes a member of the gamma-glutamylcyclotransferase family of proteins. The encoded protein has been shown to promote neuronal differentiation by deglycination of the Notch receptor, which prevents receptor maturation and inhibits Notch signaling. This protein may also play a role in the unfolded protein response, and in regulation of glutathione levels and oxidative balance in the cell. Elevated expression of this gene may indicate increased risk of cancer recurrence among breast and ovarian cancer patients. [provided by RefSeq, Sep 2016]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 50.8 kDa
• AA Sequence: MKQESAAPNTPPTSQSPTPSAQFPR NDGDPQALWIFGYGSLVWRPDFAYS DSRVGFVRGYSRRFWQGDTFHRGSD KMPGRVVTLLEDHEGCTWGVAYQVQ GEQVSKALKYLNVREAVLGGYDTKE VTFYPQDAPDQPLKALAYVATPQNP GYLGPAPEEAIATQILACRGFSGHN LEYLLRLADFMQLCGPQAQDEHLAA IVDAVGTMLPCFCPTEQALALV
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: CHAC1 ChaC glutathione specific gamma-glutamylcyclotransferase 1 [ Homo sapiens (human) ]
• Official Symbol: CHAC1
• Synonyms: CHAC1; ChaC glutathione specific gamma-glutamylcyclotransferase 1; ChaC Glutathione Specific Gamma-Glutamylcyclotransferase 1; Gamma-GCT Acting On Glutathione Homolog 1; Blocks Notch Protein; Gamma-GCG 1; Botch; Glutathione-Specific Gamma-Glutamylcyclotransferase 1; ChaC, Cation Transport Regulator Homolog 1 (E. Coli); ChaC, Cation Transport Regulator Homolog 1; Cation Transport Regulator-Like Protein 1; ChaC, Cation Transport Regulator-Like 1; EC 2.3.2.-
• Gene ID: 79094
• mRNA Refseq: NM_024111
• Protein Refseq: NP_077016
• MIM: 614587
• UniProt ID: Q9BUX1