Recombinant Human CSF2 therapeutic protein
Cat.No. : | CSF2-P035H |
Product Overview : | Recombinant Human Colony Stimulating Factor 2 is a human recombinant granulocyte macrophage colony-stimulating factor (GM-CSF) expressed in yeast. It is a glycoprotein that is 127 residues. Substitution of Leu23 leads to a difference from native protein. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of granulocytes and macrophages. The active form of the protein is found extracellularly as a homodimer. This gene has been localized to a cluster of related genes at chromosome region 5q31, which is known to be associated with interstitial deletions in the 5q- syndrome and acute myelogenous leukemia. Other genes in the cluster include those encoding interleukins 4, 5, and 13. The expression product is the active ingredient of Immunex, Leucomax and Leukine. |
Source : | Yeast |
Species : | Human |
Molecular Mass : | 14.4 kDa |
Protein length : | 127 aa |
AA Sequence : | APARSPSPSTQPWEHVNAIQEALRL LNLSRDTAAEMNETVEVISEMFDLQ EPTCLQTRLELYKQGLRGSLT KLKGPLTMMASHYKQHCPPTPETSC ATQIITFESFKENLKDFLLVIPFDC WEPVQE |
Endotoxin : | < 1.0 EU per μg of the protein |
Purity : | >95% |
Storage : | Can be stored at +4 centigrade short term (1-2weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoidrepeated freezing and thawing cycles. |
Gene Name : | CSF2 colony stimulating factor 2 (granulocyte-macrophage) [ Homo sapiens ] |
Official Symbol : | CSF2 |
Synonyms : | CSF2; colony stimulating factor 2 (granulocyte-macrophage); granulocyte-macrophage colony-stimulating factor; GM CSF; GMCSF; granulocyte macrophage colony stimulating factor; molgramostin; sargramostim; CSF; colony-stimulating factor; granulocyte-macrophage colony stimulating factor; MGC131935; MGC138897; |
Gene ID : | 1437 |
mRNA Refseq : | NM_000758 |
Protein Refseq : | NP_000749 |
MIM : | 138960 |
UniProt ID : | P04141 |
Chromosome Location : | 5q23-q31 |
Pathway : | Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem; Calcineurin-regulated NFAT-dependent transcription in lymphocytes, organism-specific biosystem; Calcium signaling in the CD4+ TCR pathway, organism-specific biosystem; Cytokine Signaling in Immune system, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; |
Function : | cytokine activity; granulocyte macrophage colony-stimulating factor receptor binding; growth factor activity; protein binding; |
Products Types
◆ Recombinant Protein | ||
CSF2-155C | Active Recombinant Human CSF2 Protein | +Inquiry |
CSF2-28H | Active Recombinant Human CSF2 Protein (Ala18-Glu144), N-His tagged, Animal-free, Carrier-free | +Inquiry |
Csf2-391C | Active Recombinant Mouse Csf2 Protein (125 aa) | +Inquiry |
CSF2-493H | Recombinant Human CSF2 Protein | +Inquiry |
CSF2-45P | Active Recombinant Porcine CSF2 Protein | +Inquiry |
◆ Lysates | ||
CSF2-1008MCL | Recombinant Mouse CSF2 cell lysate | +Inquiry |
CSF2-740RCL | Recombinant Rat CSF2 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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