Recombinant Human DDX4 Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | DDX4-2675H |
Product Overview : | DDX4 MS Standard C13 and N15-labeled recombinant protein (NP_077726) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
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Description : | DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is a homolog of VASA proteins in Drosophila and several other species. The gene is specifically expressed in the germ cell lineage in both sexes and functions in germ cell development. Multiple transcript variants encoding different isoforms have been found for this gene. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 79.3 kDa |
AA Sequence : | MGDEDWEAEINPHMSSYVPIFEKDR YSGENGDNFNRTPASSSEMDDGPSR RDHFMKSGFASGRNFGNRDAGECNK RDNTSTMGGFGVGKSFGNRGFSNSR FEDGDSSGFWRESSNDCEDNPTRNR GFSKRGGYRDGNNSEASGPYRRGGR GSFRGCRGGFGLGSPNNDLDPDECM QRTGGLFGSRRPVLSGTGNGDTSQS RSGSGSERGGYKGLNEEVITGSGKN SWKSEAEGGESSDTQGPKVTYIPPP PPEDEDSIFAHYQTGINFDKYDTIL VEVSGHDAPPAILTFEEANLCQTLN NNIAKAGYTKLTPVQKYSIPIILAG RDLMACAQTGSGKTAAFLLPILAHM MHDGITASRFKELQEPECIIVAPTR ELVNQIYLEARKFSFGTCVRAVVIY GGTQLGHSIRQIVQGCNILCATPGR LMDIIGKEKIGLKQIKYLVLDEADR MLDMGFGPEMKKLISCPGMPSKEQR QTLMFSATFPEEIQRLAAEFLKSNY LFVAVGQVGGACRDVQQTVLQVGQF SKREKLVEILRNIGDERTMVFVETK KKADFIATFLCQEKISTTSIHGDRE QREREQALGDFRFGKCPVLVATSVA ARGLDIENVQHVINFDLPSTIDEYV HRIGRTGRCGNTGRAISFFDLESDN HLAQPLVKVLTDAQQDVPAWLEEIA FSTYIPGFSGSTRGNVFASVDTRKG KSTLNTAGFSSSQAPNPVDDESWDT RTRPLEQKLISEEDLAANDILDYKD DDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | DDX4 DEAD-box helicase 4 [ Homo sapiens (human) ] |
Official Symbol : | DDX4 |
Synonyms : | DDX4; DEAD (Asp-Glu-Ala-Asp) box polypeptide 4; DEAD/H (Asp Glu Ala Asp/His) box polypeptide 4; probable ATP-dependent RNA helicase DDX4; VASA; vasa homolog; DEAD box protein 4; DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 4; MGC111074; |
Gene ID : | 54514 |
mRNA Refseq : | NM_024415 |
Protein Refseq : | NP_077726 |
MIM : | 605281 |
UniProt ID : | Q9NQI0 |
Products Types
◆ Recombinant Protein | ||
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Ddx4-2507M | Recombinant Mouse Ddx4 Protein, Myc/DDK-tagged | +Inquiry |
DDX4-468H | Recombinant Human DDX4 Protein, MYC/DDK-tagged | +Inquiry |
DDX4-1043R | Recombinant Rhesus Macaque DDX4 Protein, His (Fc)-Avi-tagged | +Inquiry |
DDX4-2486H | Recombinant Human DDX4 Protein, GST-tagged | +Inquiry |
◆ Lysates | ||
DDX4-7006HCL | Recombinant Human DDX4 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionDDX4 protein expression is used as a biomarker for germ cell development and certain reproductive diseases, aiding in diagnosis and prognosis.
Yes, DDX4 protein plays an essential role in the development of both male and female gametes, making it a crucial factor in reproductive health.
DDX4 protein is involved in the regulation of oocyte and embryo development, and its dysregulation can impact fertility and reproductive outcomes.
DDX4 protein expression can be assessed using immunohistochemistry, western blotting, and other molecular techniques in clinical settings.
Yes, genetic mutations in DDX4 protein have been linked to certain forms of infertility and germ cell tumors.
Customer Reviews (3)
Write a reviewTheir prompt assistance and willingness to go above and beyond to ensure my success have been immensely valuable.
This protein has proven to be an invaluable asset in my experiments, enabling accurate and precise measurements with exceptional sensitivity.
Its purity, stability, and consistency are unparalleled, ensuring reliable and reproducible results in my research.
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