Recombinant Human DNM1 protein, His-tagged

• Cat.No.: DNM1-2822H
• Product Overview: Recombinant Human DNM1 protein(Q05193)(2-245aa), fused to N-terminal His tag, was expressed in E. coli.

Specification

• Source: E. coli
• Species: Human
• Tag: His
• Form: If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
  If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
• Molecular Mass: 32.2 kDa
• Protein length: 2-245aa
• AA Sequence: GNRGMEDLIPLVNRLQDAFSAIGQN ADLDLPQIAVVGGQSAGKSSVLENF VGRDFLPRGSGIVTRRPLVLQLVNA TTEYAEFLHCKGKKFTDFEEVRLEI EAETDRVTGTNKGISPVPINLRVYS PHVLNLTLVDLPGMTKVPVGDQPPD IEFQIRDMLMQFVTKENCLILAVSP ANSDLANSDALKVAKEVDPQGQRTI GVITKLDLMDEGTDARDVLENKLLP LRRGYIGVVNRSQKDIDGK
• Purity: Greater than 85% as determined by SDS-PAGE.
• Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
• Reconstitution: Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20°C/-80°C. Our default final concentration of glycerol is 50%.

Gene Information

• Gene Name: DNM1 dynamin 1 [ Homo sapiens ]
• Official Symbol: DNM1
• Synonyms: DNM1; dynamin 1; DNM; dynamin-1
• Gene ID: 1759
• mRNA Refseq: NM_001005336
• Protein Refseq: NP_001005336
• MIM: 602377
• UniProt ID: Q05193

Reviews

09/06/2022

Precise protein quantification, ensures data accuracy in our experiments.

05/26/2021

Accurate mass spectrometry, essential for precise proteomics analysis.

03/06/2021

Efficient peptide synthesis, accelerates our peptide research efficiently.

Q&As

How does DNM1 contribute to the development and maintenance of neural networks?

DNM1 contributes to the formation and maintenance of neural circuits, essential for brain function.

What role does DNM1 play in endocytosis and membrane trafficking within cells?

DNM1 plays a key role in endocytosis, facilitating membrane trafficking and cellular transport processes.

What are the mechanisms by which DNM1 modulates synaptic plasticity and learning?

DNM1 regulates synaptic plasticity, crucial for learning and memory formation.

How do alterations in DNM1 expression or function affect neurodegenerative diseases?

Changes in DNM1 function can influence the progression of neurodegenerative diseases, affecting neuronal health and connectivity.

How does DNM1 (Dynamin 1) regulate synaptic vesicle recycling and neurotransmitter release in neurons?

DNM1 is crucial for synaptic vesicle recycling, controlling neurotransmitter release at synapses.

How does DNM1 influence cellular signaling pathways, particularly in the nervous system?

DNM1 impacts cellular signaling in neurons, influencing various neuronal activities and responses.

What is the impact of DNM1 mutations on neurological disorders, such as epilepsy?

Mutations in DNM1 are linked to neurological conditions like epilepsy, affecting synaptic function.