Recombinant Human DUSP4 Protein, Myc/DDK-tagged

• Cat.No.: DUSP4-105H
• Product Overview: Recombinant protein of human dual specificity phosphatase 4 (DUSP4), transcript variant 1 with a C-Myc/DDK tag was expressed in HEK293T.

Specification

• Source: HEK293T
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 42.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Gene Information

• Gene Name: DUSP4 dual specificity phosphatase 4 [ Homo sapiens (human) ]
• Official Symbol: DUSP4
• Synonyms: DUSP4; dual specificity phosphatase 4; TYP; HVH2; MKP2; MKP-2; dual specificity protein phosphatase 4; MAP kinase phosphatase 2; VH1 homologous phosphatase 2; dual specificity protein phosphatase hVH2; mitogen-activated protein kinase phosphatase 2; serine/threonine specific protein phosphatase; EC 3.1.3.16; EC 3.1.3.48
• Gene ID: 1846
• mRNA Refseq: NM_001394
• Protein Refseq: NP_001385
• MIM: 602747
• UniProt ID: Q13115

Reviews

08/16/2022

The protein composition was stable and concentrated, allowing me to obtain satisfactory experimental results.

07/21/2022

Very good after-sales service to get my experiments going!

02/04/2022

The technician modified my experimental protocol so that my experiment went smoothly.

Q&As

How is DUSP4 involved in the signaling pathway?

DUSP4 inactivates MAPKs by dephosphorylating them and thus performs an important function in the MAPK signaling pathway

What is DUSP4 also known as?

DUSP4 also known as mitogen-activated protein kinase phosphatase 2

Which membrane is recommended for DUSP4 protein for WB?

You can choose PVDF membrane.

What diseases is DUSP4 involved in?

DUSP4 is involved in diseases such as laryngeal, breast and colorectal cancer

What are the effects of overexpression of DUSP4?

In colon cancer, overexpression of DUSP4 may lead to increased proliferation of tumor cells through stimulation of growth-promoting genes such as Myc and cell cycle protein D1