Recombinant Human ELAC1 293 Cell Lysate
Cat.No. : | ELAC1-6639HCL |
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Description : | Antigen standard for elaC homolog 1 (E. coli) (ELAC1) is a lysate prepared from HEK293T cells transiently transfected with a TrueORF gene-carrying pCMV plasmid and then lysed in RIPA Buffer. Protein concentration was determined using a colorimetric assay. The antigen control carries a C-terminal Myc/DDK tag for detection. |
Source : | HEK 293 cells |
Species : | Human |
Components : | This product includes 3 vials: 1 vial of gene-specific cell lysate, 1 vial of control vector cell lysate, and 1 vial of loading buffer. Each lysate vial contains 0.1 mg lysate in 0.1 ml (1 mg/ml) of RIPA Buffer (50 mM Tris-HCl pH7.5, 250 mM NaCl, 5 mM EDTA, 50 mM NaF, 1% NP40). The loading buffer vial contains 0.5 ml 2X SDS Loading Buffer (125 mM Tris-Cl, pH6.8, 10% glycerol, 4% SDS, 0.002% Bromophenol blue, 5% beta-mercaptoethanol). |
Size : | 0.1 mg |
Storage Instruction : | Store at -80°C. Minimize freeze-thaw cycles. After addition of 2X SDS Loading Buffer, the lysates can be stored at -20°C. Product is guaranteed 6 months from the date of shipment. |
Applications : | ELISA, WB, IP. WB: Mix equal volume of lysates with 2X SDS Loading Buffer. Boil the mixture for 10 min before loading (for membrane protein lysates, incubate the mixture at room temperature for 30 min). Load 5 ug lysate per lane. |
Gene Name : | ELAC1 elaC homolog 1 (E. coli) [ Homo sapiens ] |
Official Symbol : | ELAC1 |
Synonyms : | ELAC1; elaC homolog 1 (E. coli); elaC (E. coli) homolog 1; zinc phosphodiesterase ELAC protein 1; D29; tRNA Z (short form); RNase Z 1; tRNase ZS; tRNase Z 1; deleted in Ma29; ribonuclease Z 1; tRNA 3 endonuclease 1; elaC homolog protein 1; tRNA 3 processing endoribonuclease; FLJ59261; |
Gene ID : | 55520 |
mRNA Refseq : | NM_018696 |
Protein Refseq : | NP_061166 |
MIM : | 608079 |
UniProt ID : | Q9H777 |
Chromosome Location : | 18q21 |
Pathway : | RNA transport, organism-specific biosystem; RNA transport, conserved biosystem; |
Function : | endonuclease activity; endoribonuclease activity, producing 5-phosphomonoesters; hydrolase activity; metal ion binding; |
Products Types
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionELAC1 protein is involved in maintaining mitochondrial function, and mutations in the ELAC1 gene can contribute to mitochondrial disorders.
Clinical trials investigating the role of ELAC1 protein in mitochondrial disorders are currently underway, aiming to develop targeted therapies.
As of now, there are no specific treatments targeting ELAC1 protein for mitochondrial disorders, but ongoing research may lead to future therapeutic approaches.
In addition to pontocerebellar hypoplasia and mitochondrial disorders, mutations in ELAC1 gene have been linked to infantile hypertrophic cardiomyopathy.
ELAC1 protein plays a role in mitochondrial RNA processing, which is essential for proper cardiac function. Mutations in ELAC1 gene can lead to cardiomyopathy.
Customer Reviews (3)
Write a reviewThe ELAC1 Protein exhibits remarkable stability and functionality, making it an optimal choice for a wide range of applications in various fields.
Its exceptional purity and consistency have consistently yielded reliable and reproducible results, ensuring the accuracy and reliability of my research outcomes.
Their prompt and knowledgeable assistance has been instrumental in overcoming hurdles and has significantly contributed to the success of my research.
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