Recombinant Human ELAC1, His-tagged
Cat.No. : | ELAC1-96H |
Product Overview : | Recombinant human ELAC1 was expressed in E.coli and purified by using conventional chromatography techniques. |
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Description : | ELAC1 also known as Zinc phosphodiesterase ELAC protein 1. Zinc phosphodiesterase, which displays some tRNA 3"-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3"-trailer from precursor tRNA. |
Source : | E.coli |
Species : | Human |
Tag : | His |
Form : | Liquid. In Phosphate buffered saline (pH7.4) containing 10% glycerol, 1mM DTT |
Molecular Mass : | 42.4 kDa (386aa) confirmed by MALDI-TOF |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MGSMSMDVTF LGTGAAYPSP TRGASAVVLR CEGECWLFDC GEGTQTQLMK SQLKAGRITK IFITHLHGDH FFGLPGLLCT ISLQSGSMVS KQPIEIYGPV GLRDFIWRTM ELSHTELVFH YVVHELVPTA DQCPAEELKE FAHVNRADSP PKEEQGRTIL LDSEENSYLL FDDEQFVVKA FRLFHRIPSF GFSVVEKKRP GKLNAQKLKD LGVPPGPAYG KLKNGISVVL ENGVTISPQD VLKKPIVGRK ICILGDCSGV VGDGGVKLCF EADLLIHEAT LDDAQMDKAK EHGHSTPQMA ATFAKLCRAK RLVLTHFSQR YKPVALAREG ETDGIAELKK QAESVLDLQE VTLAEDFMVI SIPIKK |
Purity : | >80% by SDS - PAGE |
Storage : | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
Concentration : | 0.5mg/ml (determined by Absorbance at 280nm) |
Gene Name : | ELAC1 elaC homolog 1 (E. coli) [ Homo sapiens ] |
Official Symbol : | ELAC1 |
Synonyms : | ELAC1; elaC homolog 1 (E. coli); elaC (E. coli) homolog 1; zinc phosphodiesterase ELAC protein 1; D29; tRNA Z (short form); RNase Z 1; tRNase ZS; tRNase Z 1; deleted in Ma29; ribonuclease Z 1; tRNA 3 endonuclease 1; elaC homolog protein 1; tRNA 3 processing endoribonuclease; FLJ59261; |
Gene ID : | 55520 |
mRNA Refseq : | NM_018696 |
Protein Refseq : | NP_061166 |
MIM : | 608079 |
UniProt ID : | Q9H777 |
Chromosome Location : | 18q21 |
Pathway : | RNA transport, organism-specific biosystem; RNA transport, conserved biosystem; |
Function : | endonuclease activity; endoribonuclease activity, producing 5-phosphomonoesters; hydrolase activity; metal ion binding; |
Products Types
◆ Recombinant Protein | ||
ELAC1-3227H | Recombinant Human ELAC1 Protein, GST-tagged | +Inquiry |
ELAC1-2729M | Recombinant Mouse ELAC1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Elac1-520M | Recombinant Mouse Elac1 Protein, MYC/DDK-tagged | +Inquiry |
ELAC1-944Z | Recombinant Zebrafish ELAC1 | +Inquiry |
ELAC1-5120M | Recombinant Mouse ELAC1 Protein | +Inquiry |
◆ Lysates | ||
ELAC1-6639HCL | Recombinant Human ELAC1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionELAC1 protein is involved in maintaining mitochondrial function, and mutations in the ELAC1 gene can contribute to mitochondrial disorders.
Clinical trials investigating the role of ELAC1 protein in mitochondrial disorders are currently underway, aiming to develop targeted therapies.
As of now, there are no specific treatments targeting ELAC1 protein for mitochondrial disorders, but ongoing research may lead to future therapeutic approaches.
In addition to pontocerebellar hypoplasia and mitochondrial disorders, mutations in ELAC1 gene have been linked to infantile hypertrophic cardiomyopathy.
ELAC1 protein plays a role in mitochondrial RNA processing, which is essential for proper cardiac function. Mutations in ELAC1 gene can lead to cardiomyopathy.
Customer Reviews (3)
Write a reviewThe ELAC1 Protein exhibits remarkable stability and functionality, making it an optimal choice for a wide range of applications in various fields.
Its exceptional purity and consistency have consistently yielded reliable and reproducible results, ensuring the accuracy and reliability of my research outcomes.
Their prompt and knowledgeable assistance has been instrumental in overcoming hurdles and has significantly contributed to the success of my research.
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