Recombinant Human IFN gamma
Cat.No. : | IFNg-31H |
Product Overview : | Human IFN gamma was produced in yeast and therefore does not have endotoxin, is naturally folded, and post-translationally modified. |
- Specification
- Gene Information
- Related Products
Description : | Interferon-gamma (IFN-gamma) is a dimerized soluble cytokine that is the only member of the type II class of interferons. This interferon was originally called macrophage-activating factor, a term now used to describe a larger family of proteins to which IFN-gamma belongs. IFN-gamma, or type II interferon, is a cytokine that is critical for innate and adaptive immunity against viral and intracellular bacterial infections and for tumor control. Aberrant IFN-gamma expression is associated with a number of autoinflammatory and autoimmune diseases. The importance of IFN-gamma in the immune system stems in part from its ability to inhibit viral replication directly, but, most important, derives from its immunostimulatory and immunomodulatory effects. IFN-gamma is produced predominantly by natural killer (NK) and natural killer T (NKT) cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte (CTL) effector T cells once antigen-specific immunity develops. |
Source : | Yeast |
Species : | Human |
Form : | Lyophilized |
Molecular Mass : | 16.8 kDa |
AA Sequence : | QDPYVKEAEN LKKYFNAGHS DVADNGTLFL GILKNWKEES DRKIMQSQIV SFYFKLFKNF KDDQSIQKSV ETIKEDMNVK FFNSNKKKRD DFEKLTNYSV TDLNVQRKAI HELIQVMAEL SPAAKTGKRK RSQMLFRGRR ASQ (143) |
Applications : | The IFN gamma protein can be used in cell culture, as a IFN gamma ELISA Standard, and as a Western Blot Control. |
Storage : | -20 C |
Gene Name : | IFNG interferon, gamma [ Homo sapiens ] |
Official Symbol : | IFNg |
Synonyms : | IFNG; interferon, gamma; interferon gamma; IFN-gamma; immune interferon; IFG; IFI; |
Gene ID : | 3458 |
mRNA Refseq : | NM_000619 |
Protein Refseq : | NP_000610 |
MIM : | 147570 |
UniProt ID : | P01579 |
Chromosome Location : | 12q14 |
Pathway : | ATF-2 transcription factor network, organism-specific biosystem; African trypanosomiasis, organism-specific biosystem; African trypanosomiasis, conserved biosystem; Allograft rejection, organism-specific biosystem; Allograft rejection, conserved biosystem; Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem; |
Function : | cytokine activity; interferon-gamma receptor binding; |
Products Types
◆ Recombinant Protein | ||
Ifng-078M | Active Recombinant Mouse Ifng Protein | +Inquiry |
IFNG-497H | Recombinant Human IFNG Protein | +Inquiry |
Ifng-379I | Active Recombinant Mouse Ifng Protein (134 aa) | +Inquiry |
IFNG-380I | Active Recombinant Human IFNG Protein (144 aa) | +Inquiry |
IFNG-084H | Active Recombinant Human IFNG Protein | +Inquiry |
◆ Lysates | ||
IFNG-1536RCL | Recombinant Rat IFNG cell lysate | +Inquiry |
IFNG-1797MCL | Recombinant Mouse IFNG cell lysate | +Inquiry |
IFNG-1007FCL | Recombinant Ferret IFNG cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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