Recombinant Human IL13RA1 Protein, C-His-tagged
Cat.No. : | IL13RA1-075H |
Product Overview : | Recombinant Human IL13RA1 Protein with C-His tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | The Th2 cytokine Interleukin-13 (IL-13) plays a critical role in allergen-induced airway hyper-responsiveness (AHR). Two different receptors exist for IL-13, designated IL-13Ra1 and 2. IL-13Ra1 exists as a heterodimer of IL-13Ra1 and IL-4Ra as a signaling subunit, whereas IL-13Ra2 acts as a decoy receptor for IL-13. Furthermore, TNFa or IL-4 stimulation induces IL-13Ra2 upregulation, while IL-13Ra1 is constitutively expressed. Cell surface localization of IL-13Ra2 abrogates IL-13 signaling, thus IL-13 induced translocation of the receptor from the cytoplasm provides a mechanism for negative-feedback of IL-13 signaling. IL-13Ra1 expression is predominant in B cells, monocytes and T cells, whereas IL-13Ra2 expression is highest in glioma cells. |
Source : | E. coli |
Species : | Human |
Tag : | C-His |
Molecular Mass : | ~35 kDa |
AA Sequence : | GGGGAAPTETQPPVTNLSVSVENLC TVIWTWNPPEGASSNCSLWYFSHFG DKQDKKIAPETRRSIEVPLNERICL QVGSQCSTNESEKPSILVEKCISPP EGDPESAVTELQCIWHNLSYMKCSW LPGRNTSPDTNYTLYYWHRSLEKIH QCENIFREGQYFGCSFDLTKVKDSS FEQHSVQIMVKDNAGKIKPSFNIVP LTSRVKPDPPHIKNLSFHNDDLYVQ WENPQNFISRCLFYEVEVNNSQTET HNVFYVQEAKCENPEFERNVENTSC FMVPGVLPDTLNTVRIRVKTNKLCY EDDKLWSNWSQEMSIGKKRNST |
Purity : | Transferred into competent cells and the supernatant was purified by NI column affinity chromatography and the purity is > 85% (by SDS-PAGE). |
Notes : | For research use only, not for use in diagnostic procedure. |
Storage : | Store at 4 centigrade short term. Aliquot and store at -20 centigrade long term. Avoid freeze-thaw cycles. |
Concentration : | ≥0.5 mg/mL |
Storage Buffer : | PBS, 4M Urea, pH7.4 |
Gene Name : | IL13RA1 interleukin 13 receptor, alpha 1 [ Homo sapiens (human) ] |
Official Symbol : | IL13RA1 |
Synonyms : | IL13RA1; interleukin 13 receptor, alpha 1; interleukin-13 receptor subunit alpha-1; CD213a1; CD213a1 antigen; IL 13Ra; IL13 receptor alpha 1 chain; NR4; CT19; IL-13RA1; IL-13R-alpha-1; IL-13R subunit alpha-1; cancer/testis antigen 19; IL13 receptor alpha-1 chain; IL-13 receptor subunit alpha-1; bB128O4.2.1 (interleukin 13 receptor, alpha 1); CD213A1; IL-13Ra; |
Gene ID : | 3597 |
mRNA Refseq : | NM_001560 |
Protein Refseq : | NP_001551 |
MIM : | 300119 |
UniProt ID : | P78552 |
Products Types
◆ Recombinant Protein | ||
IL13RA1-308H | Recombinant Human IL13RA1 Protein, His-tagged | +Inquiry |
IL13RA1-506H | Recombinant Human IL13RA1 Protein, C13 and N15 Labeled | +Inquiry |
Il13ra1-61M | Recombinant Mouse Il13ra1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Il13ra1-310M | Recombinant Mouse Il13ra1 Protein, Fc-tagged | +Inquiry |
IL13RA1-3483H | Recombinant Human IL13RA1, His-tagged | +Inquiry |
◆ Lysates | ||
IL13RA1-2627MCL | Recombinant Mouse IL13RA1 cell lysate | +Inquiry |
IL13RA1-1443RCL | Recombinant Rat IL13RA1 cell lysate | +Inquiry |
IL13RA1-2550HCL | Recombinant Human IL13RA1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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