Recombinant Human IL13RA1 Protein, His-tagged

• Cat.No.: IL13RA1-308H
• Product Overview: Recombinant human IL13RA1 protein with His tag was expressed in HEK293.

Specification

• Description: The protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4.
• Source: HEK293
• Species: Human
• Tag: His
• Form: Lyophilized
• Molecular Mass: 38 kDa
• Protein Length: 427
• AA Sequence: MEWPARLCGLWALLLCAGGGGGGGG AAPTETQPPVTNLSVSVENLCTVIW TWNPPEGASSNCSLWYFSHFGDKQD KKIAPETRRSIEVPLNERICLQVGS QCSTNESEKPSILVEKCISPPEGDP ESAVTELQCIWHNLSYMKCSWLPGR NTSPDTNYTLYYWHRSLEKIHQCEN IFREGQYFGCSFDLTKVKDSSFEQH SVQIMVKDNAGKIKPSFNIVPLTSR VKPDPPHIKNLSFHNDDLYVQWENP QNFISRCLFYEVEVNNSQTETHNVF YVQEAKCENPEFERNVENTSCFMVP GVLPDTLNTVRIRVKTNKLCYEDDK LWSNWSQEMSIGKKRNSTLYITMLL IVPVIVAGAIIVLLLYLKRLKIIIF PPIPDPGKIFKEMFGDQNDDTLHWK KYDIYEKQTKEETDSVVLIENLKKA SQ
• Purity: > 98%
• Applications: WB; ELISA; FACS; FC
• Stability: This bioreagent is stable at 4 centigrade (short-term) and -70 centigrade(long-term). After reconstitution, sample may be stored at 4 centigrade for 2-7 days and below -18 centigrade for future use.
• Storage: At -20 centigrade.
• Concentration: 1 mg/mL
• Storage Buffer: PBS (pH 7.4-7.5). Sterile-filtered colorless solution.
• Reconstitution: Reconstitute in sterile distilled H2O to no less than 100 μg/mL; dilute reconstituted stock further in other aqueous solutions if needed. Please review COA for lot-specific instructions. Final measurements should be determined by the end-user for optimal performance.

Gene Information

• Gene Name: IL13RA1 interleukin 13 receptor, alpha 1 [ Homo sapiens (human) ]
• Official Symbol: IL13RA1
• Synonyms: IL13RA1; interleukin 13 receptor, alpha 1; interleukin-13 receptor subunit alpha-1; CD213a1; CD213a1 antigen; IL 13Ra; IL13 receptor alpha 1 chain; NR4; CT19; IL-13RA1; IL-13R-alpha-1; IL-13R subunit alpha-1; cancer/testis antigen 19; IL13 receptor alpha-1 chain; IL-13 receptor subunit alpha-1; bB128O4.2.1 (interleukin 13 receptor, alpha 1); CD213A1; IL-13Ra
• Gene ID: 3597
• mRNA Refseq: NM_001560
• Protein Refseq: NP_001551
• MIM: 300119
• UniProt ID: P78552