Recombinant Human INS Protein
Cat.No. : | INS-61H |
Product Overview : | Recombinant Human INS Protein was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes insulin, a peptide hormone that plays a vital role in the regulation of carbohydrate and lipid metabolism. After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified, including insulin-dependent diabetes mellitus, permanent neonatal diabetes diabetes mellitus, maturity-onset diabetes of the young type 10 and hyperproinsulinemia. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. |
Source : | E. coli |
Species : | Human |
Form : | Liquid. In 20 mM Tris-HCl, 150 mM NaCl, pH 8.0. |
Molecular Mass : | ~12.8 kDa |
AA Sequence : | HHHHHHMDDDDKFVNQHLCGSHLVE ALYLVCGERGFFYTPKTRREAEDLQ VGQVELGGGPGAGSLQPLALNAVEV LKREPLNYLPLEGSLQKRGIVEQCC TSICSLYQLENYCN |
Purity : | >90% |
Storage : | Short Term Storage at 4 centigrade, Long Term, please prepare aliquots with 20% glycerol and store at -20 to -80 centigrade. Avoid freeze/thaw cycles. |
Concentration : | 0.34 mg/ml |
Official Full Name : | Insulin |
Gene Name : | INS insulin [ Homo sapiens (human) ] |
Official Symbol : | INS |
Synonyms : | IDDM; ILPR; IRDN; IDDM1; IDDM2; PNDM4; MODY10 |
Gene ID : | 3630 |
mRNA Refseq : | NM_000207 |
Protein Refseq : | NP_000198 |
MIM : | 176730 |
UniProt ID : | P01308 |
Products Types
◆ Recombinant Protein | ||
INS-856H | Recombinant Human INS Protein, His-tagged | +Inquiry |
INS-369C | Recombinant Cynomolgus Monkey INS Protein, His (Fc)-Avi-tagged | +Inquiry |
INS-1187H | Recombinant Human INS Protein, His (Fc)-Avi-tagged | +Inquiry |
INS-2689C | Recombinant Chicken INS Protein, His-tagged | +Inquiry |
INS-321 | Synthesis Human Proinsulin C-Peptide (55-89), bioactive peptide hormone | +Inquiry |
◆ Native Protein | ||
INS-512D | Native Bovine INS | +Inquiry |
INS-5435B | Native Bovine Insulin | +Inquiry |
◆ Lysates | ||
INS-5195HCL | Recombinant Human INS 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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