Recombinant Human INS Protein (Phe25-Thr54, Gly90-Thr110), N-His tagged
Cat.No. : | INS-2368H |
Product Overview : | Recombinant human INS (Phe25-Thr54, Gly90-Thr110) protein fused with the N-His tag was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes insulin, a peptide hormone that plays a vital role in the regulation of carbohydrate and lipid metabolism. After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified, including insulin-dependent diabetes mellitus, permanent neonatal diabetes diabetes mellitus, maturity-onset diabetes of the young type 10 and hyperproinsulinemia. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. |
Source : | E. coli |
Species : | Human |
Tag : | N-His |
Molecular Mass : | 11.8 kDa |
Protein Length : | Phe25-Thr54, Gly90-Thr110 |
Purity : | >90 % as determined by SDS-PAGE. |
Notes : | For research use only. |
Storage : | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt. |
Storage Buffer : | Supplied as solution form in PBS or lyophilized from PBS. |
Reconstitution : | Reconstitute in sterile water for a stock solution. |
Shipping : | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
Gene Name : | INS insulin [ Homo sapiens (human) ] |
Official Symbol : | INS |
Synonyms : | INS; insulin; proinsulin; ILPR; IRDN; IDDM2; MODY10; |
Gene ID : | 3630 |
mRNA Refseq : | NM_000207 |
Protein Refseq : | NP_000198 |
MIM : | 176730 |
UniProt ID : | P01308 |
Products Types
◆ Recombinant Protein | ||
INS-5100H | Recombinant Human INS Protein, GST-tagged | +Inquiry |
INS-14H | Active Recombinant Human Insulin, Low Endotoxin, Media Grade | +Inquiry |
INS-1187H | Recombinant Human INS Protein, His (Fc)-Avi-tagged | +Inquiry |
INS-2689C | Recombinant Chicken INS Protein, His-tagged | +Inquiry |
INS-856H | Recombinant Human INS Protein, His-tagged | +Inquiry |
◆ Native Protein | ||
INS-512D | Native Bovine INS | +Inquiry |
INS-5435B | Native Bovine Insulin | +Inquiry |
◆ Lysates | ||
INS-5195HCL | Recombinant Human INS 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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