Recombinant Human KDM4E Protein, Strep II-tagged
Cat.No. : | KDM4E-140H |
Product Overview : | Active recombinant N-terminal Strep II-tagged human KDM4E protein (2-337) was expressed in E. coli. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this intronless gene is a member of a large family of histone lysine demethylases, which use oxygen and 2-oxoglutarate to demethylate di- and trimethylated lys9 of histone H3. Derepression of genes by demethylases is sometimes involved in viral infection or carcinogenesis, so inhibitors of these enzymes are desired. |
Source : | E. coli |
Species : | Human |
Tag : | Strep II |
Molecular Mass : | 40.8 kDa |
Protein length : | 2-337 |
Purity : | ≥75% estimated by SDS-PAGE |
Unit Definition : | One unit is defined as the amount of enzyme required to produce 1 nmol of NADH per minute at 37 centigrade in 50 mM HEPES buffer, pH 7.4, containing 50 mM sodium chloride, 1 mM ascorbic acid, 50 μM ferrous ammonium sulfate, 1 mM NAD+, 1 mM α-ketoglutarate, 0.1 μM FDH, and 125 μM H3K9me3 peptide. |
Stability : | ≥ 6 months |
Storage : | At -80 centigrade. |
Storage Buffer : | 20 mM HEPES, pH 7.4, and 150 mM sodium chloride |
Gene Name : | KDM4E lysine demethylase 4E [ Homo sapiens (human) ] |
Official Symbol : | KDM4E |
Synonyms : | KDM4E; lysine demethylase 4E; KDM5E; JMJD2E; KDM4DL; lysine-specific demethylase 4E; KDM4D-like protein; [histone H3]-trimethyl-L-lysine(9) demethylase 4E; lysine (K)-specific demethylase 4E; EC 1.14.11.66 |
Gene ID : | 390245 |
mRNA Refseq : | NM_001161630 |
Protein Refseq : | NP_001155102 |
MIM : | 616581 |
UniProt ID : | B2RXH2 |
Products Types
◆ Recombinant Protein | ||
KDM4E-009H | Recombinant Human KDM4E Protein, Strep II-tagged | +Inquiry |
KDM4E-119H | Recombinant Human KDM4E(1-336) Protein, N-His-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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