Recombinant Human NCR2 protein, lFc-tagged

• Cat.No.: NCR2-0579H
• Product Overview: Recombinant Human NCR2 protein(Gln22-Ala192), fused with lFc tag, was expressed in HEK293.

Specification

• Source: HEK293
• Species: Human
• Tag: lFc
• Form: Lyophilized from 0.22 μm filtered solution in 50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5. Normally trehalose is added as protectant before lyophilization.
• Molecular Mass: This protein carries a llama IgG2b Fc tag at the C-terminus.The protein has a calculated MW of 46.5 kDa. The protein migrates as 66-76 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Proteinlength: Gln22-Ala192
• Endotoxin: Less than 0.01 EU per μg by the LAL method.
• Purity: >90% as determined by SDS-PAGE.
• Storage: Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.

Gene Information

• Gene Name: NCR2 natural cytotoxicity triggering receptor 2 [ Homo sapiens ]
• Official Symbol: NCR2
• Synonyms: NCR2; natural cytotoxicity triggering receptor 2; LY95, lymphocyte antigen 95 (activating NK receptor; NK p44); CD336; NK p44; NK cell-activating receptor; NK cell activating receptor (NKp44); natural killer cell p44-related protein; lymphocyte antigen 95 (activating NK-receptor; NK-p44); lymphocyte antigen 95 homolog (activating NK-receptor; LY95; NKP44; NK-p44; dJ149M18.1
• Gene ID: 9436
• mRNA Refseq: NM_001199509
• Protein Refseq: NP_001186438
• MIM: 604531
• UniProt ID: O95944

Reviews

01/27/2023

The NCR2 proteins purchased from your company is suitable for ELISA.

08/12/2022

The technical expert communicated with me in time to understand the progress of my experiment and gave me suggestions for improvement.

07/20/2022

The high quality of the purchased protein helped me to obtain satisfactory experimental results.

Q&As

Where NCR2 is expressed?

NCR2 is only expressed on the surface of activated natural killer (NK) cells.

What is the relationship between NCR2 and DAP12?

NCR2 interacts with DAP12.

What function does NCR2 have?

NCR2 proteins function as cytotoxic activation receptors that enhance the efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.