Recombinant Human NR2F2 cell lysate

• Cat.No.: NR2F2-1217HCL

Specification

• Species: Human
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: NR2F2 nuclear receptor subfamily 2, group F, member 2 [ Homo sapiens ]
• Official Symbol: NR2F2
• Synonyms: NR2F2; nuclear receptor subfamily 2, group F, member 2; ARP1, TFCOUP2; COUP transcription factor 2; COUP TFII; COUPTFB; NF E3; SVP40; COUP transcription factor II; apolipoprotein AI regulatory protein 1; apolipoprotein A-I regulatory protein 1; ADP-ribosylation factor related protein 1; chicken ovalbumin upstream promoter transcription factor 2; chicken ovalbumin upstream promoter-transcription factor I; chicken ovalbumin upstream promoter-transcription factor II variant 1; chicken ovalbumin upstream promoter-transcription factor II variant 2; chicken ovalbumin upstream promoter-transcription factor II variant 3; ARP1; NF-E3; NR2F1; TFCOUP2; COUPTFII; MGC117452
• Gene ID: 7026
• mRNA Refseq: NM_001145155
• Protein Refseq: NP_001138627
• MIM: 107773
• UniProt ID: P24468
• Chromosome Location: 15q26
• Pathway: Developmental Biology, organism-specific biosystem; FOXA1 transcription factor network, organism-specific biosystem; Nuclear Receptors, organism-specific biosystem; Regulation of Telomerase, organism-specific biosystem; Transcriptional Regulation of White Adipocyte Differentiation, organism-specific biosystem
• Function: DNA binding; ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; metal ion binding; protein binding; protein homodimerization activity; receptor activity; retinoic acid binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding transcription factor activity; steroid hormone receptor activity; transcription corepressor activity; zinc ion binding

Reviews

12/08/2022

The short half-life and high clearance properties of this recombinant protein provide great advantages for its use in emergency medical Settings because of its rapid onset of action and rapid clearance from the body.

02/10/2022

Purity and biological activity of the proteins were excellent, which provided a strong guarantee for the accuracy of the experimental results and deserved praise.

10/24/2020

Production process of this recombinant protein is very environmentally friendly, maximizing the use of resources and minimizing the consumption of energy by optimizing the process and equipment.

Q&As

What is the function of NR2F2 protein in the nervous system?

NR2F2 protein is involved in neurodevelopment, synapse formation and neuroprotection processes in the nervous system, and has an important impact on the normal function maintenance of the nervous system.

Is NR2F2 protein involved in metabolic regulation?

Yes, NR2F2 protein is involved in regulating fat metabolism, glucose metabolism and cholesterol metabolism, and plays an important role in the maintenance of energy balance and metabolic homeostasis.

Are there pathogenic mutations associated with the NR2F2 protein?

Yes, some disease-causing mutations associated with the NR2F2 protein have been reported that may lead to developmental defects, cardiovascular disease, and other related diseases.

What is the role of NR2F2 protein in the immune system?

NR2F2 protein regulates the development, differentiation, and function of T and B cells in the immune system. It plays an important role in the regulation of the immune response.

What are the post-translational modifications of NR2F2 protein?

NR2F2 protein is regulated by various post-translational modifications such as phosphorylation, acetylation, and ubiquitination, which can affect its stability, activity, and function.

Is NR2F2 protein related to heart development and function?

Yes, the NR2F2 protein plays an important role in heart development and cardiovascular disease. It is involved in early cardiac development, determination of the fate of heart cells, and regulation of heart function.