Recombinant Human NR2F2 Protein, GST-tagged

• Cat.No.: NR2F2-25H
• Product Overview: Human NR2F2 full-length ORF ( NP_066285.1, 1 a.a. - 414 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a member of the steroid thyroid hormone superfamily of nuclear receptors. The encoded protein is a ligand inducible transcription factor that is involved in the regulation of many different genes. Alternate splicing results in multiple transcript variants.
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Form: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
• Molecular Mass: 72 kDa
• AA Sequence: MAMVVSTWRDPQDEVPGSQGSQASQ APPVPGPPPGAPHTPQTPGQGGPAS TPAQTAAGGQGGPGGPGSDKQQQQQ HIECVVCGDKSSGKHYGQFTCEGCK SFFKRSVRRNLSYTCRANRNCPIDQ HHRNQCQYCRLKKCLKVGMRREAVQ RGRMPPTQPTHGQFALTNGDPLNCH SYLSGYISLLLRAEPYPTSRFGSQC MQPNNIMGIENICELAARMLFSAVE WARNIPFFPDLQITDQVALLRLTWS ELFVLNAAQCSMPLHVAPLLAAAGL HASPMSADRVVAFMDHIRIFQEQVE KLKALHVDSAEYSCLKAIVLFTSDA CGLSDVAHVESLQEKSQCALEEYVR SQYPNQPTRFGKLLLRLPSLRTVSS SVIEQLFFVRLVGKTPIETLIRDML LSGSSFNWPYMAIQ
• Purity: >85%
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.

Gene Information

• Gene Name: NR2F2 nuclear receptor subfamily 2 group F member 2 [ Homo sapiens (human) ]
• Official Symbol: NR2F2
• Synonyms: ARP1,COUP-TFII,COUPTFB,MGC117452,SVP40,TFCOUP2
• Gene ID: 7026
• mRNA Refseq: NM_021005.2
• Protein Refseq: NP_066285.1
• MIM: 107773
• UniProt ID: P24468

Reviews

12/08/2022

The short half-life and high clearance properties of this recombinant protein provide great advantages for its use in emergency medical Settings because of its rapid onset of action and rapid clearance from the body.

02/10/2022

Purity and biological activity of the proteins were excellent, which provided a strong guarantee for the accuracy of the experimental results and deserved praise.

10/24/2020

Production process of this recombinant protein is very environmentally friendly, maximizing the use of resources and minimizing the consumption of energy by optimizing the process and equipment.

Q&As

What is the function of NR2F2 protein in the nervous system?

NR2F2 protein is involved in neurodevelopment, synapse formation and neuroprotection processes in the nervous system, and has an important impact on the normal function maintenance of the nervous system.

Is NR2F2 protein involved in metabolic regulation?

Yes, NR2F2 protein is involved in regulating fat metabolism, glucose metabolism and cholesterol metabolism, and plays an important role in the maintenance of energy balance and metabolic homeostasis.

Are there pathogenic mutations associated with the NR2F2 protein?

Yes, some disease-causing mutations associated with the NR2F2 protein have been reported that may lead to developmental defects, cardiovascular disease, and other related diseases.

What is the role of NR2F2 protein in the immune system?

NR2F2 protein regulates the development, differentiation, and function of T and B cells in the immune system. It plays an important role in the regulation of the immune response.

What are the post-translational modifications of NR2F2 protein?

NR2F2 protein is regulated by various post-translational modifications such as phosphorylation, acetylation, and ubiquitination, which can affect its stability, activity, and function.

Is NR2F2 protein related to heart development and function?

Yes, the NR2F2 protein plays an important role in heart development and cardiovascular disease. It is involved in early cardiac development, determination of the fate of heart cells, and regulation of heart function.