Recombinant Human RBP3 Protein (Pro19-Leu320), His tagged
Cat.No. : | RBP3-6156H |
Product Overview : | Recombinant human RBP3 (Pro19-Leu320) fused with His tag was expressed in E. coli. |
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Description : | Retinol-binding proteins (RBP) are a family of proteins with diverse functions. They are carrier proteins that bind retinol. Retinol and retinoic acid play crucial roles in the modulation of gene expression and overall development of an embryo. However, deficit or excess of either one of these substances can cause early embryo mortality or developmental malformations. Regulation of transport and metabolism of retinol necessary for a successful pregnancy is accomplished via RBP. Retinol binding proteins have been identified within the uterus, embryo, and extraembryonic tissue of the bovine, ovine, and porcine, clearly indicating that RBP plays a role in proper retinol exposure to the embryo and successful transport at the maternal-fetal interface. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Lyophilized powder/frozen liquid |
Molecular Mass : | 32.9 kDa |
Protein Length : | Pro19-Leu320 |
Purity : | > 90 % as determined by SDS-PAGE |
Notes : | For research use only. |
Storage : | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt. |
Storage Buffer : | Supplied as solution form in PBS, pH 7.5 or lyophilized from PBS, pH 7.5. |
Reconstitution : | Reconstitute in sterile water for a stock solution. |
Shipping : | They are shipped out with dry ice/blue ice unless customers require otherwise. |
Gene Name : | RBP3 retinol binding protein 3, interstitial [ Homo sapiens (human) ] |
Official Symbol : | RBP3 |
Synonyms : | RBP3; retinol binding protein 3, interstitial; retinol-binding protein 3; D10S64; D10S65; D10S66; interphotoreceptor retinoid-binding protein; IRBP; RBPI; |
Gene ID : | 5949 |
mRNA Refseq : | NM_002900 |
Protein Refseq : | NP_002891 |
MIM : | 180290 |
UniProt ID : | P10745 |
Products Types
◆ Recombinant Protein | ||
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Rbp3-5426M | Recombinant Mouse Rbp3 Protein, Myc/DDK-tagged | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionRBP3 contributes to the efficient transport and delivery of retinoids to photoreceptor cells, facilitating their uptake for visual processes.
Potential therapeutic strategies targeting RBP3 could address vision-related disorders involving retinoid metabolism, making it a promising focus for drug development.
RBP3 interacts with binding partners, including retinoids like 11-cis-retinal, influencing its role in retinoid transport and uptake.
RBP3 is predominantly localized within the retina, specifically in photoreceptor cells and the retinal pigment epithelium (RPE).
RBP3 actively regulates retinoid homeostasis and participates in the visual cycle, critical for maintaining optimal visual function.
Retinol-Binding Protein 3 (RBP3) plays a crucial role in supporting visual function and regulating retinoid metabolism.
Dysregulation or abnormal expression of RBP3 is associated with vision-related disorders such as retinitis pigmentosa.
Customer Reviews (3)
Write a reviewGel electrophoresis consistently displayed well-defined bands, affirming the product's purity and reliability.
Replicating results underscored the reliability and relevance of the product's effects.
The user-friendly design of the product made it accessible to researchers with varying levels of expertise.
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