Recombinant Human RCC1 Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | RCC1-2204H |
Product Overview : | SNHG3 MS Standard C13 and N15-labeled recombinant protein (NP_001041664) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
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Description : | Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP, and thereby plays an important role in RAN-mediated functions in nuclear import and mitosis. Contributes to the generation of high levels of chromosome-associated, GTP-bound RAN, which is important for mitotic spindle assembly and normal progress through mitosis. Via its role in maintaining high levels of GTP-bound RAN in the nucleus, contributes to the release of cargo proteins from importins after nuclear import. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 45 kDa |
AA Sequence : | MSPKRIAKRRSPPADAIPKSKKVKV SHRSHSTEPGLVLTLGQGDVGQLGL GENVMERKKPALVSIPEDVVQAEAG GMHTVCLSKSGQVYSFGCNDEGALG RDTSVEGSEMVPGKVELQEKVVQVS AGDSHTAALTDDGRVFLWGSFRDNN GVIGLLEPMKKSMVPVQVQLDVPVV KVASGNDHLVMLTADGDLYTLGCGE QGQLGRVPELFANRGGRQGLERLLV PKCVMLKSRGSRGHVRFQDAFCGAY FTFAISHEGHVYGFGLSNYHQLGTP GTESCFIPQNLTSFKNSTKSWVGFS GGQHHTVCMDSEGKAYSLGRAEYGR LGLGEGAEEKSIPTLISRLPAVSSV ACGASVGYAVTKDGRVFAWGMGTNY QLGTGQDEDAWSPVEMMGKQLENRV VLSVSSGGQHTVLLVKDKEQSTRTR PLEQKLISEEDLAANDILDYKDDDD KV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | RCC1 regulator of chromosome condensation 1 [ Homo sapiens (human) ] |
Official Symbol : | RCC1 |
Synonyms : | RCC1; regulator of chromosome condensation 1; CHC1, chromosome condensation 1; regulator of chromosome condensation; cell cycle regulatory protein; SNHG3-RCC1 readthrough transcript; guanine nucleotide-releasing protein; CHC1; RCC1-I; SNHG3-RCC1; |
Gene ID : | 1104 |
mRNA Refseq : | NM_001048199 |
Protein Refseq : | NP_001041664 |
MIM : | 179710 |
UniProt ID : | P18754 |
Products Types
◆ Recombinant Protein | ||
RCC1-1868H | Recombinant Human RCC1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Rcc1-019M | Recombinant Mouse Rcc1 Protein, MYC/DDK-tagged | +Inquiry |
RCC1-1326H | Recombinant Human RCC1 Protein, GST-Tagged | +Inquiry |
RCC1-181H | Recombinant Human RCC1 Protein, Strep-tagged | +Inquiry |
RCC1-2229H | Recombinant Human RCC1, GST-tagged | +Inquiry |
◆ Lysates | ||
RCC1-2445HCL | Recombinant Human RCC1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionThe expression level of RCC1 protein may be related to the stage and clinicopathological features of lung cancer.
RCC1 protein is involved in regulating the progress of cellular mitosis by regulating the formation of new nuclear pores, the decomposition of nuclear membranes, and the separation of chromosomes.
RCC1 protein has some potential in tumor markers, but more research is needed to verify its clinical application value.
Yes, the RCC1 protein may play an important role in DNA damage repair, helping to maintain genome stability.
Mutations in the RCC1 protein are associated with neurological diseases (such as Parkinson's disease) and autoimmune diseases (such as systemic lupus erythematosus).
The RCC1 protein may be involved in the initiation and progression of immune diseases by affecting the activity of immune cells and the balance of immune responses.
Customer Reviews (3)
Write a reviewStability of tRCC1 is highly praised, and its ability to maintain its structural and functional stability even in various extreme environments is truly impressive.
The green production process of RCC1 focuses on sustainable development and maximizes the utilization of energy and resources by optimizing the production process and equipment.
This short half-life and high clearance properties of this RCC1 allow its rapid action and rapid clearance in vivo, reducing the risk of side effects.
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