Recombinant Human RXRB Protein (G294-A528), His tagged

• Cat.No.: RXRB-0971H
• Product Overview: Recombinant Human 6His-TEV-RXRB(G294-A528) Protein was expressed in E. coli.

Specification

• Description: Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE).
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid
• Protein Length: G294-A528
• Endotoxin: < 0.01 EU per μg of the protein
• Purity: 90%
• Stability: Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade.
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: Supplied as sterile 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol
• Shipping: It is shipped out with blue ice.

Gene Information

• Gene Name: RXRB retinoid X receptor, beta [ Homo sapiens (human) ]
• Official Symbol: RXRB
• Synonyms: RXRB; retinoid X receptor, beta; retinoic acid receptor RXR-beta; H 2RIIBP; NR2B2; nuclear receptor subfamily 2 group B member 2; RCoR 1; retinoid X nuclear receptor beta; MHC class I promoter binding protein; DAUDI6; RCoR-1; H-2RIIBP; MGC1831
• Gene ID: 6257
• mRNA Refseq: NM_021976
• Protein Refseq: NP_068811
• MIM: 180246
• UniProt ID: P28702

Reviews

10/19/2022

Timely support for protein expression optimization, appreciated assistance.

04/08/2021

High-quality protein characterization, fundamental for our research.

05/25/2018

Accurate protein structural analysis, indispensable for our investigations.

Q&As

How do environmental factors like diet and sunlight exposure affect the activity and expression of RXRB?

Environmental factors like diet and sunlight alter RXRB activity, impacting its role in skin health and metabolic processes.

What are the effects of RXRB dysregulation on cancer development and progression?

Dysregulation of RXRB can contribute to the development and progression of various cancers.

How does RXRB influence the immune response, especially in autoimmune and inflammatory diseases?

RXRB modulates the immune system, affecting autoimmune and inflammatory responses.

How does RXRB contribute to metabolic regulation, particularly in lipid metabolism and obesity?

RXRB is crucial in lipid metabolism, influencing processes related to obesity and metabolic health.

What role does RXRB play in skin health and the development of skin disorders?

RXRB plays a key role in maintaining skin health and is involved in the pathology of skin disorders.

What is the impact of RXRB on neurodevelopment and neurodegenerative diseases?

RXRB impacts neurodevelopment and is implicated in the progression of neurodegenerative diseases.

How does RXRB interact with retinoic acid and other ligands to regulate gene expression?

RXRB binds retinoic acid and other ligands to regulate genes involved in development, metabolism, and cell differentiation.