Recombinant Human RXRG protein, His & T7-tagged
Cat.No. : | RXRG-1081H |
Product Overview : | Recombinant Human RXRG aa. (Pro12~Ala220 (Accession # P48443) fused with N-terminal His & T7 tag was produced in E. coli cells. |
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Description : | This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the antiproliferative effects of retinoic acid (RA). This receptor forms dimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene is expressed at significantly lower levels in non-small cell lung cancer cells. Alternatively spliced transcript variants have been described. |
Source : | E. coli |
Species : | Human |
Tag : | His & T7 |
Form : | Freeze-dried powder |
Molecular Mass : | Predicted Molecular Mass: 26.0kDa. |
Protein length : | Pro12~Ala220 (Accession # P48443) |
Endotoxin : | <1.0EU per 1µg (determined by the LAL method) |
Purity : | >95% |
Characteristic : | The isoelectric point is 9.5. |
Applications : | SDS-PAGE; WB; ELISA; IP. |
Stability : | The thermal stability is described by the loss rate of the target protein. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. (Referring from China Biological Products Standard, which was calculated by the Arrhenius equation.) The loss of this protein is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
Storage buffer : | Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl. |
Reconstitution : | Reconstitute in sterile PBS, pH7.2-pH7.4. |
Gene Name : | RXRG retinoid X receptor gamma [ Homo sapiens (human) ] |
Official Symbol : | RXRG |
Synonyms : | RXRG; retinoid X receptor gamma; RXRC; NR2B3; retinoic acid receptor RXR-gamma; nuclear receptor subfamily 2 group B member 3 |
Gene ID : | 6258 |
mRNA Refseq : | NM_001256571.1 |
Protein Refseq : | NP_001243500.1 |
UniProt ID : | P48443 |
Products Types
◆ Recombinant Protein | ||
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RXRG-4867R | Recombinant Rat RXRG Protein, His (Fc)-Avi-tagged | +Inquiry |
RXRG-1932H | Recombinant Human RXRG Protein, His (Fc)-Avi-tagged | +Inquiry |
RXRG-3878R | Recombinant Rhesus Macaque RXRG Protein, His (Fc)-Avi-tagged | +Inquiry |
RXRG-120H | Recombinant Human RXRG, GST-tagged | +Inquiry |
◆ Lysates | ||
RXRG-2097HCL | Recombinant Human RXRG 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionGenetic mutations in RXRG can disrupt its regulatory roles, leading to various developmental and metabolic disorders.
RXRG is key in regulating lipid and glucose metabolism, playing a role in metabolic homeostasis.
RXRG is essential in embryonic development and organ formation, guiding cell fate decisions.
RXRG functions as a nuclear receptor, regulating gene expression in response to ligand binding.
Targeting RXRG in therapy offers potential in treating metabolic syndromes and degenerative diseases.
It interacts with retinoids to modulate vitamin A metabolism, influencing cellular differentiation and proliferation.
It influences immune function by affecting the development and differentiation of immune cells.
Customer Reviews (3)
Write a reviewAids in groundbreaking discoveries, highly recommended.
Outstanding protein analysis, a research asset.
Enables data-driven decisions in our research.
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