Recombinant Human SLAMF8, His-tagged

• Cat.No.: SLAMF8-2694H
• Product Overview: Recombinant Human SLAMF8 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Source: E.coli
• Species: Human
• Tag: His
• Protein length: 23-233aa
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: SLAMF8 SLAM family member 8 [ Homo sapiens ]
• Official Symbol: SLAMF8
• Synonyms: SLAMF8; SLAM family member 8; BLAME; CD353; SBBI42; BCM-like membrane protein; B lymphocyte activator macrophage expressed; B-lymphocyte activator macrophage expressed; FLJ20442; MGC129578
• Gene ID: 56833
• mRNA Refseq: NM_020125
• Protein Refseq: NP_064510
• MIM: 606620
• UniProt ID: Q9P0V8
• Chromosome Location: 1q23.1
• Function: receptor activity

Reviews

10/19/2021

Perfect for biological assays.

03/03/2021

Product works as expected.

06/20/2020

Very reliable, worth the price.

Q&As

How is SLAMF8 implicated in inflammatory and autoimmune conditions?

Dysregulation of SLAMF8 can contribute to inflammatory and autoimmune diseases.

Are there potential therapeutic interventions targeting SLAMF8?

Therapeutic interventions could potentially target SLAMF8 to modulate immune responses in various diseases.

What role does SLAMF8 play in the regulation of immune responses?

It acts as an inhibitory receptor, modulating immune cell activation and cytokine production.

What are the molecular mechanisms governing SLAMF8 activity?

SLAMF8 activity is governed by interactions with other cell surface receptors and intracellular signaling pathways.

In which immune cells is SLAMF8 predominantly expressed?

SLAMF8 is predominantly found in myeloid cells, like macrophages and dendritic cells.

What is the primary function of SLAMF8 in the immune system?

SLAMF8 regulates immune responses, particularly in myeloid cells.

How does SLAMF8 contribute to immune cell signaling?

It participates in cell-cell signaling, influencing immune cell activation and function.