| Description : |
This gene encodes a sodium/bile acid cotransporter. This transporter is the primary mechanism for uptake of intestinal bile acids by apical cells in the distal ileum. Bile acids are the catabolic product of cholesterol metabolism, so this protein is also critical for cholesterol homeostasis. Mutations in this gene cause primary bile acid malabsorption (PBAM); muatations in this gene may also be associated with other diseases of the liver and intestines, such as familial hypertriglyceridemia (FHTG). |
| Source : |
Wheat Germ (in vitro) |
| Species : |
Human |
| Form : |
Liquid |
| Molecular Mass : |
38.3kDa |
| AA Sequence : |
MNDPNSCVDNATVCSGASCVVPESN FNNILSVVLSTVLTILLALVMFSMG CNVEIKKFLGHIKRPWGICVGFLCQ FGIMPLTGFILSVAFDILPLQAVVV LIIGCCPGGTASNILAYWVDGDMDL SVSMTTCSTLLALGMMPLCLLIYTK MWVDSGSIVIPYDNIGTSLVALVVP VSIGMFVNHKWPQKAKIILKIGSIA GAILIVLIAVVGGILYQSAWIIAPK LWIIGTIFPVAGYSLGFLLARIAGL PWYRCRTVAFETGMQNTQLCSTIVQ LSFTPEELNVVFTFPLIYSIFQLAF AAIFLGFYVAYKKCHGKNKAEIPES KENGTEPESSFYKANGGFQPDEK |
| Applications : |
Antibody Production |
| Usage : |
Heating may cause protein aggregation. Please do not heat this product before electrophoresis. |
| Notes : |
Best use within three months from the date of receipt of this protein. |
| Storage : |
Store at -80°C. Aliquot to avoid repeated freezing and thawing. |
| Storage Buffer : |
25 mM Tris-HCl of pH8.0 containing 2% glycerol. |
| Preparation : |
in vitro wheat germ expression system with proprietary liposome technology |
